Galactosidase alpha encodes a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties. [provided by RefSeq]
![Sandwich ELISA alpha-Galactosidase A/GLA Antibody Pair [HRP]](http://images.novusbio.com/fullsize/alpha-Galactosidase-A-GLA-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79386-img0001.jpg)
![Enzyme Activity alpha-Galactosidase A/GLA [Unconjugated]](http://images.novusbio.com/fullsize2/6146-gh_recombinant-human-alpha-galactosidase-a-gla-protein-cf-enzyme-activity-322023131935.jpg)
![Enzyme Activity alpha-Galactosidase A/GLA [Unconjugated]](http://images.novusbio.com/fullsize2/6146-gh_recombinant-human-alpha-galactosidase-a-gla-protein-cf-enzyme-activity-32202314939.jpg)
![SDS-PAGE alpha-Galactosidase A/GLA [Unconjugated]](http://images.novusbio.com/fullsize2/6146-gh_recombinant-human-alpha-galactosidase-a-gla-protein-cf-sds-page-322023141819.jpg)