BAFF Receptor Products

Description

B cell-activating factor receptor (BAFF-R) is a 19 kD type III membrane protein. It belongs to TNFR superfamily, also known as TNFRSF member 13C (TNFRSF13C), BAFF receptor 3 (BR3), or CD268. BAFF-R is expressed on mature B cells, B cell lymphoma, and T cell subset. BAFF-R is the major receptor for BAFF/BLys (or TALL-1, THANK) which binds to TACI and BCMA as well. The interaction of BAFF with BAFF-R promotes NF-234; B activation and plays predominant roles in B-cell maturation and survival as well as costimulates T cell activation and proliferation. TRAF3 is a BAFF-R intracellularly associated protein, which negatively regulates BAFF-R-mediated NF-234; B activation.

Bioinformatics

Entrez	115650 Human 72049 Mouse
Uniprot	AAK91826 Human NM_052945 Human NP_443177.1 Human Q96RJ3 Human Q9D8D0 Mouse
Product By Gene ID	115650
Alternate Names	B cell-activating factor receptor BAFF receptor BAFF-R BAFFRMGC138235 B-cell-activating factor receptor BLyS receptor 3 BR3 CD268 antigen CD268 CVID4 tumor necrosis factor receptor superfamily member 13C tumor necrosis factor receptor superfamily, member 13C

Research Areas for BAFF Receptor

Find related products by research area and learn more about each of the different research areas below.

Biologically Active Proteins
Cytokine Research
Immunology
Lipid and Metabolism