GAT3 Products

Description

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl negative channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-3 has been found to be localized to astrocytes within the cerebral cortex indicating that this transporter mediates GABA uptake into glial cells (Minelli et al., 1996).

Bioinformatics

Entrez	6538 Human
Uniprot	AAH36083.1 Human NP_055044 Human NP_055044.1 Human
Product By Gene ID	6538
Alternate Names	GABA Transporter 3 GABT3 GAT-3 GAT3sodium- and chloride-dependent GABA transporter 3 GAT4 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 Solute carrier family 6 member 11

Research Areas for GAT3

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Neuroscience