Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Goat Polyclonal
Species: Hu
Applications: WB
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Mu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Description
IL21 Receptor is a novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. Both IL-21R and the gc are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
Bioinformatics
Entrez |
Human Mouse |
Uniprot |
Human Human Human Human Human |
Product By Gene ID |
50615 |
Alternate Names |
- CD360 antigen
- IL-21 receptor
- IL-21R
- interleukin 21 receptor
- interleukin-21 receptor
- MGC10967
- NILR
- Novel interleukin receptor
|
Research Areas for IL-21R
Find related products by research area and learn more about each of the different research areas below.
Cytokine ResearchImmunology