ILT7/CD85g/LILRA4 Products

Description

ILT7 (immunoglobulin-like transcript 7) is a member of leukocyte immunoglobulin-like receptor (LIR or LILR) gene family, also known as CD85g and LILRA4. It contains four extracellular Ig domains. In association with Fc epsilonR1 gamma, ILT7 forms a receptor complex that transduces ITAM-mediated signals. ILT7 is specifically expressed on plasmacytoid dendritic cells (pDCs), but not on myeloid dendritic cells and other peripheral blood leukocytes. ILT7 negatively regulates the innate immune functions of human pDCs. Cross-linking 17G10.2 antibody is able to trigger ILT7 mediated signaling.

Bioinformatics

Entrez	23547 Human
Uniprot	NP_036408 Human NP_036408.3 Human P59901 Human
Product By Gene ID	23547
Alternate Names	CD85 antigen-like family member G CD85g antigen CD85g ILT-7 ILT7MGC129598 Immunoglobulin-like transcript 7 leukocyte immunoglobulin-like receptor subfamily A member 4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member4 MGC129597