Species: All-Multi
Applications: WB, Simple Western
Host: Rat Monoclonal
Species: All-Multi
Applications: WB, Simple Western
Host: Rat Monoclonal
Species: All-Multi
Applications: ELISA
Host: Rat Monoclonal
Applications: PAGE, Bioactivity
Applications: PAGE, Bioactivity
Applications: PAGE, Bioactivity
Description
Protein A is a surface protein of S.aureus which binds IgG molecules by their Fc region. In serum, the bacteria will bind IgG molecules in the wrong orientation on their surface which hinders opsonization and phagocytosis. Mutants of S. aureus lacking protein A are more efficiently phagocytosed in vitro, and mutants in infection models have diminished virulence. Due to its affinity for the Fc region of many mammalian immunoglobulins, protein A is considered a universal reagent in biochemistry and immunology.
Bioinformatics
Product By Gene ID |
3919448 |
Alternate Names |
- Immunoglobulin G binding protein A
- Immunoglobulin G binding protein A
- Immunoglobulin G binding protein A
- SPA
- SPA
- SPA
- Staphylococcal protein A
- Staphylococcal protein A
- Staphylococcal protein A
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Research Areas for Protein A
Find related products by research area and learn more about each of the different research areas below.
Epitope TagsFusion ProteinsGPCR