Species: Hu, Pm
Applications: WB, ELISA, ICC/IF, IHC, IP
Host: Mouse Monoclonal
Species: Hu
Applications: ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 4 tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain. The encoded protein belongs to a family of NEDD4-like proteins, which are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. Alternative splicing of this gene generates at least 6 transcript variants; however, the full length nature of these transcripts has not been defined.
Bioinformatics
Entrez |
Human |
Uniprot |
Human Human Human Human |
Product By Gene ID |
11059 |
Alternate Names |
- AIP5Nedd-4-like ubiquitin-protein ligase
- atrophin-1 interacting protein 5
- Atrophin-1-interacting protein 5
- DKFZp434D2111
- DKFZP434D2111
- EC 6.3.2
- EC 6.3.2.-
- hSDRP1
- NEDD4-like E3 ubiquitin-protein ligase WWP1
- TGIF-interacting ubiquitin ligase 1
- Tiul1
- TIUL1
- WW domain containing E3 ubiquitin protein ligase 1
- WW domain-containing protein 1
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