ABP1/AOC1 Antibody

Western Blot: ABP1/AOC1 Antibody [NBP1-32941] - Sample (30 ug of whole cell lysate) A: HeLa B: HepG2 7. 5% SDS PAGE, antibody diluted at 1:500.

Immunohistochemistry-Paraffin: ABP1/AOC1 Antibody [NBP1-32941] - Paraffin-embedded human human colon. KAO antibody [N1N2], N-term diluted at 1:500.

Product Discontinued

ABP1/AOC1 Antibody Summary

• Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human KAO. The exact sequence is proprietary.
• Localization: Secreted, extracellular space
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: AOC1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 85 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Immunogen affinity purified

Alternate Names for ABP1/AOC1 Antibody

• ABP
• ABP1
• amiloride binding protein 1 (amine oxidase (copper-containing))
• Amiloride-binding protein
• amiloride-sensitive amine oxidase [copper-containing]
• amiloride-sensitive amine oxidase
• AOC1
• AOC1DAOamiloride-binding protein-1
• DAO1
• Diamine Oxidase
• EC 1.4.3
• EC 1.4.3.22
• Histaminase
• KAO
• Kidney amine oxidase

Background

This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: AOC1