AG-3/AGR3 Antibody (AGR3.2)

Western Blot: AG-3/AGR3 Antibody (AGR3.2) [NBP1-45005] - Analysis of AGR3 protein by AGR3.1 and AGR3.2 antibody, and of AGR3 and AGR2 protein by AGR3.4 antibody in T47D breast cancer cell line compared to H1229 lung carcinoma cell line.

Product Discontinued

AG-3/AGR3 Antibody (AGR3.2) Summary

• Immunogen: Purified human AGR3 protein
• Specificity: The antibody AGR3.2 recognizes epitope QYSQALKKV within AGR3 (AG3) protein (19-20 kDa); secreted cytoplasmic protein which can serve as a marker of carcinogenesis.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: AGR3
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1 ug/ml
  • Immunohistochemistry 1 ug/ml
  • Immunohistochemistry-Frozen 1 ug/ml
  • Western Blot 1 ug/ml
• Theoretical MW: 20 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Cross reacts with Human.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: PBS and 0.2% (w/v) high grade BSA (protease free)
• Preservative: 0.09% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for AG-3/AGR3 Antibody (AGR3.2)

• AG3
• AG-3
• AGR3
• anterior gradient homolog 3 (Xenopus laevis)
• BCMP11
• BCMP11AG3
• Breast cancer membrane protein 11
• hAG-3member 18
• PDIA18

Background

AGR3 is a gene that encodes Anterior Gradient Homolog 3, a protein associated with breast cancer. Also known as Breat Cancer Membrane Protein 11, AG3 has a positive correlation with the expression of estrogen receptor. Its expression is negatively correlated with the expression of the EGF receptor. Because it is expressed in nearly three-quarters of breast cancer cells, it has high potential as a target for breast cancer therapy.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: AGR3