alpha 2-Macroglobulin-like 1/A2ML1 Antibody - BSA Free

Western Blot: alpha 2-Macroglobulin-like 1/A2ML1 Antibody [NBP3-42359] - Sample: Equine Esophagus lysate; Primary Ab: 1ug/ml NBP3-42359; Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody;

Western Blot: alpha 2-Macroglobulin-like 1/A2ML1 Antibody [NBP3-42359] - Sample: Recombinant alpha 2-Macroglobulin-like 1/A2ML1, Human.

• Reactivity: Hu, Eq
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 0.5 mg/ml

alpha 2-Macroglobulin-like 1/A2ML1 Antibody - BSA Free Summary

• Immunogen: Immunogen sequence: Gln1119-Thr1348 (Uniprot#: A8K2U0)
• Clonality: Polyclonal
• Host: Rabbit
• Gene: A2ML1
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.5-2ug/mL

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH7.4, 50% glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Antigen and protein A Affinity-purified

Alternate Names for alpha 2-Macroglobulin-like 1/A2ML1 Antibody - BSA Free

• A2ML1
• alpha 2Macroglobulin like 1
• alpha 2-Macroglobulin-like 1
• alpha-2-macroglobulin-like 1
• alpha-2-macroglobulin-like protein 1
• C3 and PZP-like, alpha-2-macroglobulin domain containing 9
• CPAMD9

Background

The alpha-macroglobulin (AM) superfamily of proteins contains both complement components and protease inhibitors, including A2M (MIM 103950) and A2ML1. AM proteins display a unique trap mechanism of inhibition, by which the AM inhibitor undergoes a major conformational change upon its cleavage by a protease, thus trapping the protease and blocking it from subsequent substrate binding (Galliano et al., 2006 [PubMed 16298998]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: A2ML1