Human BMP-2 ELISA Kit (Colorimetric)

Product Discontinued

Human BMP-2 ELISA Kit (Colorimetric) Summary

• Description: BMP2 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human BMP2.
• Standard Curve Range: 31.2 to 2000 pg/mL
• Sensitivity: <2 pg/mL
• Assay Type: Sandwich ELISA
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: BMP2

Applications/Dilutions

• Dilutions:
  • ELISA
  • Quantification
• Application Notes: Useful for quantification.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Human BMP-2 ELISA Kit (Colorimetric)

• BDA2
• BMP2
• BMP-2
• BMP-2A
• BMP2ABone morphogenetic protein 2A
• bone morphogenetic protein 2
• SSFSC

Background

Bone morphogenic proteins (BMPs) are members of the TGFbeta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFbeta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 (also designated OP-2) is thought to be involved in early development, as detectable expression has not been found in adult organs.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for BMP-2 ELISA Kit (KA0540)(4)

Publications using KA0540

• Boke F, Labude N, Lauria I et al. Biological Activation of Bioinert Medical High Performance Oxide Ceramics by Hydrolytically Stable Immobilization of c(RGDyK) and BMP-2. ACS Appl Mater Interfaces 2018-11-05 [PMID: 30280884]
• Cheng H, Jiang W, Phillips FM et al. Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs). J Bone Joint Surg Am. 2003-08-01 [PMID: 12925636]
• Hallahan AR, Pritchard JI, Chandraratna RA et al. BMP-2 mediates retinoid-induced apoptosis in medulloblastoma cells through a paracrine effect. Nat Med. 2003-08-01 [PMID: 12872164]
• Rao VV, Loffler C, Wozney JM, Hansmann I. The gene for bone morphogenetic protein 2A (BMP2A) is localized to human chromosome 20p12 by radioactive and nonradioactive in situ hybridization. Hum Genet. 1992-11-01 [PMID: 1487246]

FAQs for BMP-2 ELISA Kit (KA0540). (Showing 1 - 1 of 1 FAQs).

1. I am interested in Bone Morphogenic Protein 2 (BMP-2) for clinical trial in humans. I am using this protein in stem cells culture for future use in humans. Do you have BMP-2 in pharma grade that I can use for humans?
   • Our antibodies are for research purposes only unfortunately. I am sorry we cannot be of further help.

Bioinformatics

• Gene Symbol: BMP2