Immunohistochemistry-Frozen: C5b-9 Antibody (aE11) - BSA Free [NBP1-05120] - Vascular endothelia and dendritic cells of germinal center have strong and intensive label. Dilution: 1:10.
Use in Flow Cytometry reported in scientific literature (PMID:32900809).ELISA: NBP1-05120 is well suited for quantifying TCC in ELISA. WB: NBP1-05120 is not recommended for Western blotting as the epitope is destroyed during the process. IHC: TCC in various tissues by immunohistochemistry (frozen and paraffin sections). Use in ICC/IF reported in scientific literature (PMID: 27432952).
Publications
Read Publications using NBP1-05120 in the following applications:
Use in Bacteria reported in scientific literature (PMID:32900809).
Packaging, Storage & Formulations
Storage
Store at 4C in the dark.
Buffer
10mM Phosphate (pH 7.4) and 0.5M NaCl
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A or G purified
Alternate Names for C5b-9 Antibody (aE11) - BSA Free
MAC
Membrane attack complex
sC5-b9
sC5b-9
TCC
Terminal complement complex
Background
C5b-9 is also known as the terminal complement complex (TCC). The TCC consists of C5b, C6, C7, C8 and C9 and forms the membrane attack complex (MAC) as well as the non-lytic fluid-phase SC5b-9 complex (with protein S). The MAC forms channels in target cell membranes leading to cell lysis by osmotic leakage. The complexes contain neoantigens that are absent from the individual native components from which they are formed and this antibody is directed against a neoepitope exposed on C9 when incorporated into the TCC (1,2).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Publications for C5b-9 Antibody (NBP1-05120)(6)
We have publications tested in 2 confirmed species: Human, Bacteria.
We have publications tested in 5 applications: ELISA, FLOW, ICC/IF, IF/IHC, IHC-P.
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![Immunohistochemistry-Frozen: C5b-9 Antibody (aE11) - BSA Free [NBP1-05120] - Vascular endothelia and dendritic cells of germinal center have strong and intensive label. Dilution: 1:10.](http://images.novusbio.com/fullsize/C5b-9-Antibody-aE11-BSA-Free-Immunohistochemistry-Frozen-NBP1-05120-img0002.jpg "Immunohistochemistry-Frozen: C5b-9 Antibody (aE11) - BSA Free [NBP1-05120] - Vascular endothelia and dendritic cells of germinal center have strong and intensive label. Dilution: 1:10.")
