CCL22/MDC Antibody (D1) - BSA Free

Immunohistochemistry-Paraffin: CCL22/MDC Antibody (D1) [NBP3-41095] - Vector Red staining on IHC-P; Samples: Human Small Intestine Tissue; Primary Ab: 10ug/ml NBP3-41095; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Mouse IgG Monoclonal Antibody

Western Blot: CCL22/MDC Antibody (D1) [NBP3-41095] - Sample: Recombinant CCL22/MDC, Human.

• Reactivity: Hu
• Applications: WB, IHC
• Clone: D1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

CCL22/MDC Antibody (D1) - BSA Free Summary

• Immunogen: Immunized with recombinant Human CCL22/MDC (Uniprot#: O00626; Gly25-Gln93 (Uniprot#: O00626)
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: CCL22
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 5-20ug/mL
  • Immunohistochemistry-Paraffin 5-20ug/mL
  • Western Blot 0.01-2ug/mL

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.01M PBS, pH7.4, 50% glycerol
• Preservative: 0.05% Proclin 300
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for CCL22/MDC Antibody (D1) - BSA Free

• A-152E5.1
• ABCD-1
• CC chemokine STCP-1
• C-C motif chemokine 22
• CCL22
• chemokine (C-C motif) ligand 22
• DC/B-CK
• Macrophage-derived chemokine
• MDC
• MDCStimulated T-cell chemotactic protein 1
• MGC34554
• SCYA22MDC(1-69)
• small inducible cytokine A22
• small inducible cytokine subfamily A (Cys-Cys), member 22
• Small-inducible cytokine A22
• STCP-1
• stimulated T cell chemotactic protein 1

Background

Chemokines are a large family of small secreted proteins that regulate migration of white blood cells. Based on the arrangement of the first two of the four conserved cysteine residues, chemokines are classified into four subfamilies, CXC, CC, C and recently identified CX3C (1). The CC chemokines, in which the first 2 cysteines are adjacent, usually act on monocytes, T lymphocytes, and, in some cases, eosinophils, basophils, or mast cells. The CC subfamily proteins are 70 to 100 amino acids long, have 25 to 75% identity with each other, and include novel member of the CC chemokine subfamily, designated ABCD1 (SCYA22). The SCYA22 protein shares 28 to 34% identity with other CC chemokines and contains the characteristic 4-cysteine motif and 9 other highly conserved residues (2). The activated T cell-attracting CC chemokine CCL22 is expressed by stimulated B cells and mature dendritic cells (DC). Both identical and distinct proteins contribute to expression of CCL22 in DC and B cells (3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CCL22