Coagulation Factor XI Antibody [Biotin] - (Research Grade abelacimab Biosimilar)

• Reactivity: Hu
• Applications: ELISA, Flow, Func
• Clonality: Monoclonal
• Host: Human
• Conjugate: Biotin

Coagulation Factor XI Antibody [Biotin] - (Research Grade abelacimab Biosimilar) Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: F11 / Factor XI
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Gene: F11
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Functional
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Alternate Names for Coagulation Factor XI Antibody [Biotin] - (Research Grade abelacimab Biosimilar)

• Coagulation Factor XI
• EC 3.4.21
• EC 3.4.21.27
• FXIPlasma thromboplastin antecedent
• MGC141891
• PTA

Background

Factor XI encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: F11