Complement C3b Native Protein

• Reactivity: Hu
• Applications: ELISA
• Concentration: 1 mg/ml

Complement C3b Native Protein Summary

• Description: Native human C3b.
  
  

  Source:Human serum

  Amino Acid Sequence:UniProt P01024

• Preparation Method: Purified C3b from human serum - liquid
• Source: Human serum
• Protein/Peptide Type: Native Protein
• Gene: C3
• Purity: >90%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • ELISA
• Theoretical MW: 180 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >90%, by SDS-PAGE

Alternate Names for Complement C3b Native Protein

• AHUS5
• ARMD9
• ASP
• C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
• complement C3
• complement component 3
• complement component C3
• CPAMD1acylation-stimulating protein cleavage product

Background

C3 is a key component of the complement system since classical and alternative activation pathways merge at the C3 activation step when C3 is split into C3a and C3b. The molecular mass of C3 is 185 kDa and it consists of alpha and beta chains (110 kDa and 75 kDa respectively) held together by disulfide bonds (1,2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: C3
• Uniprot:
  • P01024()