CPT1B Antibody

Immunohistochemistry-Paraffin: CPT1B Antibody [NB100-1057] - (3.8ug/ml) staining of paraffin embedded Human Heart. Antibody at 3.8 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

• Reactivity: Hu
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

CPT1B Antibody Summary

• Immunogen: Peptide with sequence C-DIADLFQVPKAYS corresponding to C-Terminus according to NP_689452.1, NP_689451.1, NP_004368.1, NP_001138609.1, NP_001138607.1, NP_001138606.1, NP_001138608.1.
• Localization: Mitochondrial
• Specificity: This antibody is expected to recognise human isoforms a (NP_689452.1; NP_689451.1; NP_004368.1; NP_001138609.1; NP_001138607.1), isoform c (NP_001138606.1) and isoform d (NP_001138608.1).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: CPT1B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 3 - 5 ug/mL
  • Immunohistochemistry-Paraffin 3 - 5 ug/mL
  • Peptide ELISA Detection limit 1:16000
• Application Notes: Human heart shows staining of myocardial fibres in longitudinal section.
• Control:

  CPT1B Overexpression Lysate

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for CPT1B Antibody

• carnitine O-palmitoyltransferase 1, muscle isoform
• carnitine O-palmitoyltransferase I, mitochondrial muscle isoform
• Carnitine O-palmitoyltransferase I, muscle isoform
• carnitine palmitoyltransferase 1B (muscle)
• Carnitine palmitoyltransferase 1B
• Carnitine palmitoyltransferase I-like protein
• CPT I
• CPT1B
• CPT1M
• CPT1-M
• CPT1-MMCCPT1
• CPTI
• CPTI-M
• EC 2.3.1
• EC 2.3.1.21
• FLJ55729
• FLJ58750
• KIAA1670
• MCPT1
• M-CPT1

Background

The protein encoded by the CPT1B gene, a member of the carnitine/choline acetyltransferase family, is the rate-controllingenzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the nettransport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variantsencoding different isoforms have been found for this gene, and read-through transcripts are expressed from theupstream locus that include exons from this gene. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CPT1B Antibody (NB100-1057)(4)

Publications using NB100-1057

• Mire?tean CC, Iancu RI, Iancu DPT. et Al. Micro-RNAs, the Cornerstones of the Future of Radiobiology in Head and Neck Cancers? Curr Oncol 2022-02-02 [PMID: 35200568]
• Pusceddu S, Vernieri C, Di Maio M et al. Impact of Diabetes and Metformin Use on Enteropancreatic Neuroendocrine Tumors: Post Hoc Analysis of the CLARINET Study Cancers 2021-12-23 [PMID: 35008233]
• Aunapuu M, Kibur P, J�rveots T, Arend A. Changes in Morphology and Presence of Pinopodes in Endometrial Cells during the Luteal Phase in Women with Infertility Problems: A Pilot Study Medicina 2018-10-10 [PMID: 30344300]
• Yamazaki N, Shinohara Y, Shima A et al. Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase I. Biochim Biophys Acta 1996-06-07 [PMID: 8679700]

Bioinformatics

• Gene Symbol: CPT1B
• Entrez:
  • 1375(Human)
• Uniprot:
  • NP_004368(Human)