CRMP2 [p Thr514, p Ser518] Antibody

Product Discontinued

CRMP2 [p Thr514, p Ser518] Antibody Summary

• Immunogen: A synthetic peptide from the phosphorylated sites of human T514/S518 of CRMP-2 (DPYSL2, CRMP2, Dihydropyrimidinase-related protein 2) conjugated to an immunogenic carrier protein was used as the immunogen.
• Modification: p Thr514, p Ser518
• Localization: subcellular location: cytoplasm.; tissue specificity: ubiquitous.
• Specificity: This antibody recognises mainly phospho T514 & S518 of CRMP-2 (but also it is quite likely to recognise the unphosphorylated form).
• Clonality: Polyclonal
• Host: Rabbit
• Gene: DPYSL2
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:300-1:2000
  • Immunohistochemistry-Frozen 1:300-1:2000
  • Immunohistochemistry-Paraffin 1:300-1:2000
  • Western Blot 1:300-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Whole antisera
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Unpurified
• Reconstitution Instructions: Reconstitute with 0.1 ml sterilized water to desired concentration.

Alternate Names for CRMP2 [p Thr514, p Ser518] Antibody

• Collapsin response mediator protein 2
• CRMP-2
• CRMP2N2A3
• DHPRP2
• dihydropyrimidinase-like 2 long form
• dihydropyrimidinase-like 2
• dihydropyrimidinase-related protein 2
• DRP2collapsin response mediator protein hCRMP-2
• DRP-2ULIP-2
• ULIP2
• Unc-33-like phosphoprotein 2

Background

Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. plays a role in axon guidance, neuronal growth cone collapse and cell migration.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DPYSL2
• Entrez:
  • 1808(Human)
  • 12934(Mouse)
  • 25416(Rat)
• Uniprot:
  • Q16555(Human)