FCRL2/FcRH2 Antibody (B24) [PE]

• Reactivity: Hu
• Applications: Flow
• Clone: B24
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: PE

FCRL2/FcRH2 Antibody (B24) [PE] Summary

• Additional Information: Clone B24 was used by HLDA to establish CD designation.
• Immunogen: DNA-immunization followed by a boost with FCRL2/FcRH2 transfected cells
• Specificity: The mouse monoclonal antibody B24 recognizes an extracellular epitope of FCRL2/FcRH2, a transmembrane glycoprotein expressed mainly in mature and memory B cells.
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: FCRL2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Alternate Names for FCRL2/FcRH2 Antibody (B24) [PE]

• CD307b antigen
• CD307b
• Fc receptor homolog 2
• Fc receptor-like 2
• FcRH2
• FCRH2SPAP1B
• FCRL2
• FcR-like protein 2
• IFGP family protein 4
• IFGP4
• Immunoglobulin receptor translocation-associated protein 4
• immunoglobulin superfamily Fc receptor, gp42
• IRTA4
• IRTA4SPAP1C
• SH2 domain containing phosphatase anchor protein 1
• SH2 domain-containing phosphatase anchor protein 1Fc receptor-like protein 2
• SPAP1
• SPAP1A
• SPAP1immune receptor translocation-associated protein 4

Background

The FCRL2 gene codes for a member of the immunoglobulin receptor superfamily, a Fc receptor-like protein 2 that has five isoforms: isoform 1: 508 amino acids long, 55 kDA; isoform 2: 255 amino acids long, 27 kDA; isoform 3: 192 amino acids long, 20 kDA; isoform 4L 144 amino acids long, 15 kDA; and isoform 5: 202 amino acids long, 22 kDA. This protein is clustered on the long arm of chromosome 1 and may play a regulatory role in normal as well as neoplastic B cell development. FCRL2 is linked to leukemia, tonsillitis, hepatitis, and HIV type 1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: FCRL2