Recombinant Human Galectin-2 His Protein

SDS-Page: Recombinant Human Galectin-2 Protein [NBP1-48326] - 15% SDS-PAGE (3ug)

• Reactivity: Hu
• Applications: PAGE
• Concentration: 0.5 mg/ml

Recombinant Human Galectin-2 His Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-132 of Human Galectin-2
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MTGELEVKNM DMKPGSTLKI TGSIADGTDG FVINLGQGTD KLNLHFNPRF SESTIVCNSL DGSNWGQEQR EDHLCFSPGS EVKFTVTFES DKFKVKLPDG ELTFPNRLG HSHLSYLSVR GGFNMSSFKL KE

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: LGALS2
• Purity: >95%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 16.8 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH8.0), 0.2 M Nacl, 1 mM DTT, 10% glycerol
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >95%, by SDS-PAGE

Alternate Names for Recombinant Human Galectin-2 His Protein

• Beta-galactoside-binding lectin L-14-II
• GAL2
• Gal-2
• galectin 2
• Galectin2
• Galectin-2
• HL14gal-2
• Lactose-binding lectin 2
• lectin, galactoside-binding, soluble, 2
• LGALS2
• MGC75071
• S-Lac lectin 2

Background

LGALS2, also known as galectin2, is a soluble beta-galactoside binding lectin that modulates cell-to-cell adhesion and cell-to-extracellular matrix interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. This protein induces apoptosis in activated T cells and binds to the cytokine lymphotoxin-alpha (LTA) with possible implications in risk of myocardial infarction. Recombinant human Galectin 2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for Galectin-2 Recombinant Protein (NBP1-48326)(2)

Publications using NBP1-48326

• Kane J, Jansen M, Hendrix S et al. Anti-Galectin-2 antibody treatment reduces atherosclerotic plaque size and alters macrophage polarity Thrombosis and haemostasis 2021-12-01 [PMID: 34852377] (In vitro)
• Zhang L, Yu H, Bai Y Et al. A Neoglycoprotein-Immobilized Fluorescent Magnetic Bead Suspension Multiplex Array for Galectin-Binding Studies Molecules (Basel, Switzerland) 2021-10-14 [PMID: 34684775]

Bioinformatics

• Gene Symbol: LGALS2