GHRHR Antibody

Immunohistochemistry-Paraffin: GHRHR Antibody [NLS835] - Analysis of anti-GHRHR antibody with human pituitary, anterior.

Immunohistochemistry-Paraffin: GHRHR Antibody [NLS835] - Analysis of anti-GHRHR antibody with anterior pituitary.

Product Discontinued

GHRHR Antibody Summary

• Immunogen: Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human GHRHR.
• Epitope: 3rd cytoplasmic domain of human
• Specificity: Human GHRHR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Primate (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GHRHR
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 32 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Bat (88%), Equine (88%), Porcine (88%), Marmoset (81%), Bovine (81%), Canine (81%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for GHRHR Antibody

• GHRFR
• GHRH receptor
• GHRHR
• GRF receptor
• GRFR
• growth hormone releasing hormone receptor
• Growth hormone-releasing factor receptor
• growth hormone-releasing hormone receptor
• IGHD1B
• Little

Background

GHRHR, a Growth Hormone-Releasing Hormone Receptor, is involved in the proliferation and differentiation of somatotrophic pituitary cells and in disease. The GHRH receptor stimulates growth hormone (GH) secretion and synthesis in the pituitary. Mutations in this receptor cause either growth-hormone deficiency, resulting in dwarfism, or excessive production of the hormone, leading to gigantism. Four alternative splice variants have been identified that are tissue specific. GHRHR has been reported to be expressed primarily in the brain. ESTs have been isolated from brain and pituitary libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GHRHR
• Entrez:
  • 2692(Human)