Glutaminyl-peptide Cyclotransferase/QPCT Antibody

Western Blot: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [H00025797-B01P] - Analysis of QPCT expression in HeLa.

Western Blot: Glutaminyl-peptide Cyclotransferase/QPCT Antibody [H00025797-B01P] - Analysis of QPCT expression in transfected 293T cell line by QPCT polyclonal antibody. Lane 1: QPCT transfected lysate(39.71 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

Glutaminyl-peptide Cyclotransferase/QPCT Antibody Summary

• Immunogen: QPCT (NP_036545.1, 1 a.a. - 361 a.a.) full-length human protein. MAGGRHRRVVGTLHLLLLVAALPWASRGVSPSASAWPEEKNYHQPAILNSSALRQIAEGTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQRLQADWVLEIDTFLSQTPYGYRSFSNIISTLNPTAKRHLVLACHYDSKYFSHWNNRVFVGATDSAVPCAMMLELARALDKKLLSLKTVSDSKPDLSLQLIFFDGEEAFLHWSPQDSLYGSRHLAAKMASTPHPPGARGTSQLHGMDLLVLLDLIGAPNPTFPNFFPNSARWFERLQAIEHELHELGLLKDHSLEGRYFQNYSYGGVIQDDHIPFLRRGVPVLHLIPSPFPEVWHTMDDNEENLDESTIDNLNKILQVFVLEYLHL
• Specificity: QPCT - glutaminyl-peptide cyclotransferase (glutaminyl cyclase),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: QPCT
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Glutaminyl-peptide Cyclotransferase/QPCT Antibody

• EC 2.3.2.5
• GCT
• Glutaminyl cyclase
• glutaminyl-peptide cyclotransferase
• Glutaminyl-tRNA cyclotransferase
• Glutamyl cyclase
• QCEC
• QPCT
• sQC

Background

This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Glutaminyl-peptide Cyclotransferase/QPCT Antibody (H00025797-B01P)(2)

Publications using H00025797-B01P

• Valenti MT, Bolognin S, Zanatta C et al. Increased glutaminyl cyclase expression in peripheral blood of Alzheimer's disease patients. J Alzheimers Dis 2013-01-01 [PMID: 23207485]
• Demuth H, Schilling S, Kleinschmidt M et al. Glutaminyl Cyclase As a Diagnostic/Prognostic Indicator For Neurodegenrative Diseases. United States Patent Application 2015-09-03

Bioinformatics

• Gene Symbol: QPCT
• Entrez:
  • 25797(Human)
• Uniprot:
  • NP_036545.1(Human)