Helios Antibody (22F6) [mFluor Violet 610 SE]

Helios Antibody (22F6) [mFluor Violet 610 SE] [NBP2-37723MFV610] - Vial of mFluor Violet 610 conjugated antibody. mFluor Violet 610 is optimally excited at 421 nm by the Violet laser (405 nm) and has an emission maximum of 613 nm.

Helios Antibody (22F6) [mFluor Violet 610 SE] [NBP2-37723MFV610] - Vial of mFluor Violet 610 conjugated antibody. mFluor Violet 610 is optimally excited at 421 nm by the Violet laser (405 nm) and has an emission maximum of 613 nm.

• Reactivity: Hu, Mu
• Applications: Flow, CyTOF-ready
• Clone: 22F6
• Clonality: Monoclonal
• Host: Armenian Hamster
• Conjugate: mFluor Violet 610 SE

Helios Antibody (22F6) [mFluor Violet 610 SE] Summary

• Immunogen: Peptide coresponding to the amino acids 51-107 of Helios.
• Specificity: The armenian hamster monoclonal antibody 22F6 recognizes Helios, a transcription factor expressed in some hematopoietic stem cells, and at high levels in thymic-derived regulatory T cells.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Armenian Hamster
• Gene: IKZF2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Alternate Names for Helios Antibody (22F6) [mFluor Violet 610 SE]

• Helios
• IKAROS family zinc finger 2 (Helios)
• Ikaros family zinc finger protein 2
• IKZF2
• MGC34330
• subfamily 1A, 2 (Helios)
• zinc finger DNA binding protein Helios
• zinc finger protein Helios
• ZNF1A2
• ZNFN1A2

Background

HELIOS encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IKZF2