Hepatitis C Virus Core Antigen Antibody (C7-50) [Alexa Fluor® 647]

• Reactivity: Hu, Mu, V-Vi
• Applications: WB, ELISA, Flow, IHC, IP, ICC/IF
• Clone: C7-50
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

Hepatitis C Virus Core Antigen Antibody (C7-50) [Alexa Fluor® 647] Summary

• Immunogen: Purified HCV core-GST fusion protein (genotype 1b).
• Epitope: This antibody recognizes an epitope between amino acid residues 21-40 of HCV core protein. This sequence is conserved among different HCV strains.
• Specificity: Detects hepatitis C virus (HCV) core protein from transfected human and primate cell lines.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: POLY
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Immunofluorescence
  • Immunohistochemistry
  • Immunoprecipitation
  • Western Blot

Reactivity Notes

Human reactivity reported in literature (PMID: 16940534). Mouse reactivity reported in literature (PMID: 22984515).

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Hepatitis C Virus Core Antigen Antibody (C7-50) [Alexa Fluor® 647]

• Core protein p19
• HCcAg
• HCV core antigen
• HCV core protein

Background

Hepatitis C virus (HCV) is the primary cause of non-A, non-B hepatitis and results in most HCV-infected people developing chronic infections, liver cirrhosis and hepatocellular carcinoma. The 21 kDa core protein of HCV is well conserved among different HCV genotypes and may suppress hepatitis B virus replication in a phosphorylation dependent manner.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: POLY