Recombinant HIV-1 gp120 Protein

Product Discontinued

Recombinant HIV-1 gp120 Protein Summary

• Description: A partial recombinant protein with a His tag and corresponding to amino acids 40 - 489 of HIV-1gp120 (AY424138).
  
  

  Source: 293 cells

• Preparation Method: Mammalian cell (293) expression system
• Protein/Peptide Type: Recombinant Protein
• Gene: env

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Application Notes: This product is useful for SDS-PAGE.

Reactivity Notes

Virus

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: In PBS (25% glycerol, < 0.1% BSA)
• Preservative: No Preservative

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Recombinant HIV-1 gp120 Protein

• Envelope surface glycoprotein gp120
• gp120 glycoprotein
• gp120
• Human immunodeficiency virus 1
• SU
• Surface protein

Background

HIV-1 gp120 is a surface glycoprotein that enables viral attachment and entry into host cells. It is also involved in neurotoxicity and has been implicated in HIV-associated neurocognitive disorders. HIV-1 gp120 also induces apoptosis in neuronal cells by signaling mitochondrial-death proteins which may upregulate the death receptor, Fas. Because HIV gp120 is necessary for HIV-1 to enter CD4 cells, gp120 is one of the main targets of HIV vaccine research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: env