Human Pro-Collagen I alpha 1 DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Pro-Collagen I alpha 1 DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: COL1A1

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Pro-Collagen I alpha 1 DuoSet ELISA, 5 Plate

• Alpha-1 type I collagen
• COL1A1
• COL-IA1
• Collagen 1 alpha 1
• Collagen 1
• collagen alpha 1 chain type I
• collagen alpha-1(I) chain
• Collagen I alpha 1
• collagen of skin, tendon and bone, alpha-1 chain
• Collagen Type I Alpha 1 Chain
• collagen, type I, alpha 1
• Collagen1
• Collagen-1
• EDSARTH1
• OI4
• pro-alpha-1 collagen type 1
• Type I Procollagen Alpha 1 Chain

Background

Type I collagen is the most abundant structural protein of connective tissues such as skin, bone and tendon. It is synthesized as a procollagen molecule which is characterized by a 300 nm triple helical domain flanked by globular N- and C-terminal propeptides. The triple helical domain contains Gly-Xaa-Yaa triplets where Xaa and Yaa are frequently proline and hydroxyproline, respectively. The non-helical propeptides are removed by procollagen N- and C-proteinase activities so that the mature triple helices can self-assemble into collagen fibrils that provide tensile strength to tissues. Type I collagen is a heterotrimer that consists of two alpha 1(I) chains and one alpha 2(I) chain, although homotrimers consisting of three identical alpha 1(I) chains have also been described. This recombinant mini pro-alpha 1(I) collagen consists of a shortened alpha 1(I) chain with following domain structure from N- to C-terminus: N-propeptide, N-telopeptide, the 33 most N-terminal Gly-Xaa-Yaa repeats, the 33 most C-terminal Gly-Xaa-Yaa repeats, C-telopeptide and C-propeptide. The preparation contains a mixture of the full-length molecule, pN collagen I (alpha 1) and the C-terminal propeptide. This truncated pro-alpha 1(I) collagen is a substrate for procollagen N-proteinase and procollagen C-proteinase.

Publications for Collagen I alpha 1 (DY6220-05)(56)

Publications using DY6220-05

• Bang, J;Hwang, YL;Kim, MY;Yun, JN;Hyun, E;Chang, MY;Shin, DH;Kim, S;Lee, JH; Wrinkle-Improving Effect of Novel Peptide That Binds to Nicotinic Acetylcholine Receptor International journal of molecular sciences 2024-07-18 [PMID: 39063099] (Human)
• Pinnarò, V;Kirchberger, S;Künig, S;Gil Cantero, S;Ciardulli, MC;Della Porta, G;Blüml, S;Elbe-Bürger, A;Bochkov, V;Stöckl, J; Oxidized Phospholipids Regulate Tenocyte Function via Induction of Amphiregulin in Dendritic Cells International journal of molecular sciences 2024-07-11 [PMID: 39062855] (Human)
• Aleman, J;Ravikumar, K;Wiegand, C;Schurdak, ME;Vernetti, L;Gavlock, D;Reese, C;DeBiasio, R;LaRocca, G;Angarita, YD;Gough, A;Soto-Gutierrez, A;Behari, J;Yechoor, V;Miedel, MT;Stern, AM;Banerjee, I;Taylor, DL; A metabolic-dysfunction associated steatotic liver acinus biomimetic induces pancreatic islet dysfunction in a coupled microphysiology system bioRxiv : the preprint server for biology 2024-04-30 [PMID: 38712135] (Human)
• Calver, J;Parmar, N;Harris, G;Lithgo, R;Stylianou, P;Zetterberg, F;Gooptu, B;MacKinnon, A;Carr, S;Borthwick, L;Scott, D;Stewart, I;Slack, R;Jenkins, G;John, A; Defining the mechanism of galectin-3-mediated TGF-?1 activation and its role in lung fibrosis Journal of Biological Chemistry 2024-04-18 [PMID: 38641066] (Human)
• Klatte-Schulz, F;Bormann, N;Bonell, A;Al-Michref, J;Nguyen, HL;Klöckner, P;Thiele, K;Moroder, P;Seifert, M;Sawitzki, B;Wildemann, B;Duda, GN; Pro-Resolving Mediators in Rotator Cuff Disease: How Is the Bursa Involved? Cells 2023-12-20 [PMID: 38201221] (Human)
• Lee, KS;Kim, Y;Lee, JH;Shon, S;Kim, A;Pham, AVQ;Kim, C;Kim, DH;Kim, YK;Cho, EG; Human Probiotic Lactobacillus paracasei-Derived Extracellular Vesicles Improve Tumor Necrosis Factor-?-Induced Inflammatory Phenotypes in Human Skin Cells 2023-12-07 [PMID: 38132109] (Human)
• Siquier-Dameto, G;Boisnic, S;Boadas-Vaello, P;Verdú, E; Anti-Aging and Depigmentation Effect of a Hyaluronic Acid Mechanically Stabilized Complex on Human Skin Explants Polymers 2023-05-24 [PMID: 37299236] (Human)
• SR Trampuž, S van Riet, Å Nordling, M Ingelman-S The Role of CTGF in Liver Fibrosis Induced in 3D Human Liver Spheroids Cells, 2023-01-13;12(2):. 2023-01-13 [PMID: 36672237] (Human)
• S Kang, H Lee, SH Jun, SG Park, NG Kang Enhancement of Efficacy of Retinoids through Enhancing Retinoid-Induced RAR Activity and Inhibiting Hydroxylation of Retinoic Acid, and Its Clinical Efficacy on Photo-Aging Pharmaceutics, 2022-11-08;14(11):. 2022-11-08 [PMID: 36365229] (Human)
• G Zhu, W Chen, CY Tang, A McVicar, D Edwards, J Wang, M McConnell, S Yang, Y Li, Z Chang, YP Li Knockout and Double Knockout of Cathepsin K and Mmp9 reveals a novel function of Cathepsin K as a regulator of osteoclast gene expression and bone homeostasis International journal of biological sciences, 2022-08-29;18(14):5522-5538. 2022-08-29 [PMID: 36147479] (Mouse)
• Kartasheva-Ebertz D, Gaston J, Lair-Mehiri L, Mottez E, Buivan T, Massault P, Scatton O, Gaujoux S, Vaillant J, Pol S, Lagaye S IL-17A in Human Liver: Significant Source of Inflammation and Trigger of Liver Fibrosis Initiation. Int J Mol Sci, 2022-08-29;23(17):. 2022-08-29 [PMID: 36077175] (Human)
• FA Fadeyev, FA Blyakhman, AP Safronov, GY Melnikov, AD Nikanorova, IP Novoselova, GV Kurlyandsk Biological Impact of gamma-Fe2O3 Magnetic Nanoparticles Obtained by Laser Target Evaporation: Focus on Magnetic Biosensor Applications Biosensors, 2022-08-11;12(8):. 2022-08-11 [PMID: 36005023] (Human)
• N Xia, Y Cai, W Wang, C Bao, Y Li, Q Xie, W Xu, D Liu Association of bone-related�biomarkers with femoral neck bone strength Bmc Musculoskeletal Disorders, 2022-05-21;23(1):482. 2022-05-21 [PMID: 35597928] (Human)
• MB da Cruz, JF Marques, BF Fernandes, S Madeira, Ó Carvalho, FS Silva, ADSP da Mata, JMM Caramês Peri-implant cell response on groove and pore-textured zirconia surfaces Journal of oral biosciences, 2022-02-07;0(0):. 2022-02-07 [PMID: 35143954] (Human)
• M Piñeiro-Ra, N Flórez-Fer, O Ramil-Góme, MD Torres, H Dominguez, FJ Blanco, R Meijide-Fa, C Vaamonde-G Antifibrotic effect of brown algae-derived fucoidans on osteoarthritic fibroblast-like synoviocytes Carbohydrate polymers, 2022-01-12;282(0):119134. 2022-01-12 [PMID: 35123730] (Human)
• A Chignon, D Argaud, MC Boulanger, G Mkannez, V Bon-Baret, Z Li, S Thériault, Y Bossé, P Mathieu Genome-wide chromatin contacts of super-enhancer-associated lncRNA identify LINC01013 as a regulator of fibrosis in the aortic valve PloS Genetics, 2022-01-18;18(1):e1010010. 2022-01-18 [PMID: 35041643] (Human)
• M Blanco, N Sanz, AC Sánzhez, B Correa, RI Pérez-Mart, CG Sotelo Molecular Weight Analysis of Blue Shark (Prionace glauca) Collagen Hydrolysates by GPC-LS; Effect of High Molecular Weight Hydrolysates on Fibroblast Cultures: mRNA Collagen Type I Expression and Synthesis International Journal of Molecular Sciences, 2021-12-21;23(1):. 2021-12-21 [PMID: 35008452] (Human)
• V Vorstandle, M Laggner, D Copic, K Klas, M Direder, Y Chen, B Golabi, W Haslik, C Radtke, E Tschachler, K Hötzenecke, HJ Ankersmit, M Mildner The serine proteases dipeptidyl-peptidase 4 and urokinase are key molecules in human and mouse scar formation Nature Communications, 2021-10-29;12(1):6242. 2021-10-29 [PMID: 34716325] (Human)
• E Dzia?o, M Czepiel, K Tkacz, M Siedlar, G Kania, P B?yszczuk WNT/beta-Catenin Signaling Promotes TGF-beta-Mediated Activation of Human Cardiac Fibroblasts by Enhancing IL-11 Production International Journal of Molecular Sciences, 2021-09-17;22(18):. 2021-09-17 [PMID: 34576234] (Human)
• K Liu, P Jing, Z Liu, Y Wang, Z Han, Y Wang, Z Zheng, Y Wu, T Wang, Y Li, H Zhang, L Wang Serum levels of irisin in postmenopausal women with osteoporotic hip fractures Cytokine, 2021-09-21;148(0):155708. 2021-09-21 [PMID: 34560610] (Human)
• CM Stanton, AS Findlay, C Drake, MZ Mustafa, P Gautier, L McKie, IJ Jackson, V Vitart A mouse model of brittle cornea syndrome caused by mutation in Zfp469 Disease Models & Mechanisms, 2021-09-22;14(9):. 2021-09-22 [PMID: 34368841] (Mouse, Transgenic Mouse)
• X Zhou, LJ Backman, P Danielson Activation of NF-&kapppaB signaling via cytosolic mitochondrial RNA sensing in kerotocytes with mitochondrial DNA common deletion Scientific Reports, 2021-04-01;11(1):7360. 2021-04-01 [PMID: 33795727] (Human)
• Y Xia, L Zhen, H Li, S Wang, S Chen, C Wang, X Yang MIRLET7BHG promotes hepatocellular carcinoma progression by activating hepatic stellate cells through exosomal SMO to trigger Hedgehog pathway Cell Death & Disease, 2021-03-26;12(4):326. 2021-03-26 [PMID: 33771969] (Human)
• P Zhou, G Chu, Z Yuan, H Wang, W Zhang, Y Mao, X Zhu, W Chen, H Yang, B Li Regulation of differentiation of annulus fibrosus-derived stem cells using heterogeneous electrospun fibrous scaffolds Journal of Orthopaedic Translation, 2020-03-03;26(0):171-180. 2020-03-03 [PMID: 33437636] (Rabbit)
• A Bayer, B Wijaya, L Möbus, F Rademacher, M Rodewald, M Tohidnezha, T Pufe, D Drücke, R Gläser, J Harder Platelet-Released Growth Factors and Platelet-Rich Fibrin Induce Expression of Factors Involved in Extracellular Matrix Organization in Human Keratinocytes 22.39 Int J Mol Sci, 2020-06-20;21(12):. 2020-06-20 [PMID: 32575800] (Human)
• JH Oh, YH Joo, F Karadeniz, J Ko, CS Kong Syringaresinol Inhibits UVA-Induced MMP-1 Expression by Suppression of MAPK/AP-1 Signaling in HaCaT Keratinocytes and Human Dermal Fibroblasts Int J Mol Sci, 2020-06-01;21(11):. 2020-06-01 [PMID: 32492931] (Human)
• B Baeza-Raja, A Goodyear, X Liu, K Lam, L Yamamoto, Y Li, GS Dodson, T Takeuchi, T Kisseleva, DA Brenner, K Dabbagh Pharmacological inhibition of P2RX7 ameliorates liver injury by reducing inflammation and fibrosis PLoS ONE, 2020-06-03;15(6):e0234038. 2020-06-03 [PMID: 32492075] (Human)
• P B?yszczuk, C Zuppinger, A Costa, D Nurzynska, FD Di Meglio, M Stellato, I Agarkova, GL Smith, O Distler, G Kania Activated Cardiac Fibroblasts Control Contraction of Human Fibrotic Cardiac Microtissues by a beta-Adrenoreceptor-Dependent Mechanism Cells, 2020-05-20;9(5):. 2020-05-20 [PMID: 32443848] (Human)
• E Bigaeva, N Puerta Cav, EGD Stribos, AJ de Jong, C Biel, HAM Mutsaers, MS Jensen, R Nørregaard, AM Leliveld, IJ de Jong, JL Hillebrand, H van Goor, M Boersema, RA Bank, P Olinga Predictive Value of Precision-Cut Kidney Slices as an Ex Vivo Screening Platform for Therapeutics in Human Renal Fibrosis Pharmaceutics, 2020-05-18;12(5):. 2020-05-18 [PMID: 32443499] (Human)
• JH Oh, F Karadeniz, JI Lee, SY Park, Y Seo, CS Kong Anticatabolic and Anti-Inflammatory Effects of Myricetin 3-O-&beta-d-Galactopyranoside in UVA-Irradiated Dermal Cells via Repression of MAPK/AP-1 and Activation of TGF&beta/Smad Molecules, 2020-03-14;25(6):. 2020-03-14 [PMID: 32183404] (Human)
• M Tozzi, CE Sørensen, L Magni, NM Christense, R Bouazzi, CM Buch, M Stefanini, C Duranti, A Arcangeli, I Novak Proton Pump Inhibitors Reduce Pancreatic Adenocarcinoma Progression by Selectively Targeting H+, K+-ATPases in Pancreatic Cancer and Stellate Cells Cancers (Basel), 2020-03-10;12(3):. 2020-03-10 [PMID: 32164284] (Mouse)
• HY Lim, D Jeong, SH Park, KK Shin, YH Hong, E Kim, YG Yu, TR Kim, H Kim, J Lee, JY Cho Antiwrinkle and Antimelanogenesis Effects of Tyndallized Lactobacillus acidophilus KCCM12625P Int J Mol Sci, 2020-02-27;21(5):. 2020-02-27 [PMID: 32120828] (Human)
• K Krempaska, S Barnowski, J Gavini, N Hobi, S Ebener, C Simillion, A Stokes, R Schliep, L Knudsen, TK Geiser, M Funke-Cham &alphaAzithromycin has enhanced effects on lung fibroblasts from idiopathic pulmonary fibrosis (IPF) patients compared to controls Respir. Res., 2020-01-15;21(1):25. 2020-01-15 [PMID: 31941499] (Human)
• J Chen, P Liang, Z Xiao, MF Chen, F Gong, C Li, C Zhou, P Hong, WK Jung, ZJ Qian Antiphotoaging effect of boiled abalone residual peptide ATPGDEG on UVB-induced keratinocyte HaCaT cells Food Nutr Res, 2019-11-08;63(0):. 2019-11-08 [PMID: 31762729] (Human)
• DB Myung, HS Han, JS Shin, JY Park, HJ Hwang, HJ Kim, HS Ahn, SH Lee, KT Lee Hydrangenol Isolated from the Leaves of Hydrangea serrata Attenuates Wrinkle Formation and Repairs Skin Moisture in UVB-Irradiated Hairless Mice Nutrients, 2019-10-02;11(10):. 2019-10-02 [PMID: 31581754] (Mouse)
• B Wu, XY Huang, L Li, XH Fan, PC Li, CQ Huang, J Xiao, R Gui, S Wang Attenuation of diabetic cardiomyopathy by relying on kirenol to suppress inflammation in a diabetic rat model J. Cell. Mol. Med., 2019-09-29;0(0):. 2019-09-29 [PMID: 31565849] (Rat)
• U Baranyi, B Winter, A Gugerell, B Hegedus, C Brostjan, G Laufer, B Messner Primary Human Fibroblasts in Culture Switch to a Myofibroblast-Like Phenotype Independently of TGF Beta Cells, 2019-07-13;8(7):. 2019-07-13 [PMID: 31337073] (Human)
• HX Zhang, YN Li, XL Wang, CL Ye, XY Zhu, HP Li, T Yang, YJ Liu Probucol ameliorates EMT and lung fibrosis through restoration of SIRT3 expression Pulm Pharmacol Ther, 2019-05-11;0(0):101803. 2019-05-11 [PMID: 31085231] (Mouse)
• E Dzia?o, M Rudnik, RI Koning, M Czepiel, K Tkacz, M Baj-Krzywo, O Distler, M Siedlar, G Kania, P B?yszczuk WNT3a and WNT5a Transported by Exosomes Activate WNT Signaling Pathways in Human Cardiac Fibroblasts Int J Mol Sci, 2019-03-21;20(6):. 2019-03-21 [PMID: 30901906] (Human)
• BD Sui, J Chen, XY Zhang, T He, P Zhao, CX Zheng, M Li, CH Hu, Y Jin Gender-independent efficacy of mesenchymal stem cell therapy in sex hormone-deficient bone loss via immunosuppression and resident stem cell recovery Exp. Mol. Med., 2018-12-17;50(12):166. 2018-12-17 [PMID: 30559383] (Human)
• RH Qin, H Tao, SH Ni, P Shi, C Dai, KH Shi microRNA-29a inhibits cardiac fibrosis in Sprague-Dawley rats by downregulating the expression of DNMT3A Anatol J Cardiol, 2018-10-01;20(4):198-205. 2018-10-01 [PMID: 30297596] (Rat)
• E Raschi, CB Chighizola, L Cesana, D Privitera, F Ingegnoli, C Mastaglio, PL Meroni, MO Borghi Immune complexes containing scleroderma-specific autoantibodies induce a profibrotic and proinflammatory phenotype in skin fibroblasts Arthritis Res. Ther., 2018-08-29;20(1):187. 2018-08-29 [PMID: 30157947] (Human)
• AR Han, TG Lim, YR Song, M Jang, YK Rhee, HD Hong, MH Kim, HJ Kim, CW Cho Inhibitory Effect of Opuntia humifusa Fruit Water Extract on Solar Ultraviolet-Induced MMP-1 Expression Int J Mol Sci, 2018-08-24;19(9):. 2018-08-24 [PMID: 30149526] (Human)
• Y Kondo, J Fu, H Wang, C Hoover, JM McDaniel, R Steet, D Patra, J Song, L Pollard, S Cathey, T Yago, G Wiley, S Macwana, J Guthridge, S McGee, S Li, C Griffin, K Furukawa, JA James, C Ruan, RP McEver, KJ Wierenga, PM Gaffney, L Xia Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking JCI Insight, 2018-07-26;3(14):. 2018-07-26 [PMID: 30046013] (Human)
• J Nanchahal, C Ball, D Davidson, L Williams, W Sones, FE McCann, M Cabrita, J Swettenham, NJ Cahoon, B Copsey, E Anne Franc, PC Taylor, J Black, VS Barber, S Dutton, M Feldmann, SE Lamb Anti-Tumour Necrosis Factor Therapy for Dupuytren's Disease: A Randomised Dose Response Proof of Concept Phase 2a Clinical Trial EBioMedicine, 2018-07-06;0(0):. 2018-07-06 [PMID: 29983350] (Human)
• Q Ma, Q Liu, L Yuan, Y Zhuang Protective Effects of LSGYGP from Fish Skin Gelatin Hydrolysates on UVB-Induced MEFs by Regulation of Oxidative Stress and Matrix Metalloproteinase Activity Nutrients, 2018-03-28;10(4):. 2018-03-28 [PMID: 29597313] (Mouse)
• A Aldhahrani, J Powell, S Ladak, M Ali, S Ali, B Verdon, J Pearson, C Ward The Potential Role of Bile Acids in Acquired Laryngotracheal Stenosis Laryngoscope, 2018-02-05;0(0):. 2018-02-05 [PMID: 29399801] (ELISA Capture, Human)
• A Beierfu beta , H Dietrich, C Kremser, M Hunjadi, A Ritsch, T Rülicke, C Thomé, DS Mern Knockout of Apolipoprotein E in rabbit promotes premature intervertebral disc degeneration: A new in vivo model for therapeutic approaches of spinal disc disorders PLoS ONE, 2017-11-03;12(11):e0187564. 2017-11-03 [PMID: 29099857] (Rabbit)
• E Martínez-M, J Ibarrola, A Fernández-, E Santamaria, J Fernández-, P Rossignol, F Jaisser, N López-Andr Differential Proteomics Identifies Reticulocalbin-3 as a Novel Negative Mediator of Collagen Production in Human Cardiac Fibroblasts Sci Rep, 2017-09-22;7(1):12192. 2017-09-22 [PMID: 28939891] (Human)
• M Rogers, N Maldonado-, JD Hutcheson, C Goettsch, S Goto, I Yamada, T Faits, H Sesaki, M Aikawa, E Aikawa Dynamin-Related Protein 1 Inhibition Attenuates Cardiovascular Calcification in the Presence of Oxidative Stress Circ. Res., 2017-06-12;0(0):. 2017-06-12 [PMID: 28607103] (Human)
• X Wu, D Bian, Y Dou, Z Gong, Q Tan, Y Xia, Y Dai Asiaticoside hinders the invasive growth of keloid fibroblasts through inhibition of the GDF-9/MAPK/Smad pathway J. Biochem. Mol. Toxicol, 2017-03-27;0(0):. 2017-03-27 [PMID: 28346732] (Human)
• Development of an in vitro human liver system for interrogating nonalcoholic steatohepatitis JCI Insight, 2016-12-08;1(20):e90954. 2016-12-08 [PMID: 27942596] (Human)
• Human pancreatic cancer cells induce a MyD88-dependent stromal response to promote a tumor-tolerant immune microenvironment Cancer Res., 2016-11-18;0(0):. 2016-11-18 [PMID: 27864347] (Human)
• S Robert, T Gicquel, A Bodin, V Lagente, E Boichot Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1? or TNF-? Release from Human Hepatic Stellate Cells PLoS ONE, 2016-04-05;11(4):e0153118. 2016-04-05 [PMID: 27046197] (Human)
• Shan T, Zhang L, Zhao C, Chen W, Zhang Y, Li G Angiotensin-(1-7) and angiotensin induce the transdifferentiation of human endometrial epithelial cells in vitro. Mol Med Rep, 2014-04-09;9(6):2180-6. 2014-04-09 [PMID: 24718590] (Human)
• Martineau C, Martin-Falstrault L, Brissette L, Moreau R The atherogenic Scarb1 null mouse model shows a high bone mass phenotype. Am J Physiol Endocrinol Metab, 2013-11-19;306(1):E48-57. 2013-11-19 [PMID: 24253048] (Mouse)

Review for Collagen I alpha 1 (DY6220-05) (1)

Average Rating: 5

(Based on 1 review)

reviewed by: Patricia Carulla Martí 06/13/2023

Summary

• Sample Tested: Cell culture supernatant,HDFn culture supernatant
• Lot: p354148

FAQs for Collagen I alpha 1 (DY6220-05). (Showing 1 - 4 of 4 FAQs).

1. We are looking for an anti-Collagen antibody for Flow Cytometry (FACS) analysis in Swine sample. Would you please provide some references if there is any available as well?
   • We currently have one antibody for porcine Collagen validated in flow cytometry (catalog # NBP1-94202).
2. I am looking for anti collagen 1 antibody, I see your product calls it collagen I alpha 1 is there a difference?
   • Collagen I alpha 1 is the most common protein for the collagen 1 protein. There are other subunits as well (such as collagen 1 alpha 2…etc.).
3. The predicted molecular weight says 150kDA but the band on the gel appears at 130kDA why is that?
   • Differences between the predicted and observed MW can be affected by a number of factors including PTMs, relative charges and experimental factors. These cumulative effect of these differences can be quite substantial with larger molecules such as collagen I alpha 1.
4. How long does delivery take for your collagen 1 alpha 1 antibody?
   • Our most popular collagen I alpha 1 antibody (NB600-408) is usually in stock and ships priority overnight for next business day delivery in the U.S.

Bioinformatics

• Gene Symbol: COL1A1