Mouse IgE ELISA Kit (Colorimetric)

Product Discontinued

Mouse IgE ELISA Kit (Colorimetric) Summary

• Description: IgE (Mouse) ELISA Kit is a highly sensitive two-site enzyme-linked immunoassay for the quantitative determination of IgE in mouse biological samples.
• Standard Curve Range: 6.25 to 400 ng/mL
• Assay Type: Sandwich ELISA
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: IGHE

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: Useful for quantification. ELISA usage reported in scientific literature (PMID: 25396426).

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Mouse IgE ELISA Kit (Colorimetric)

• IgE
• immunoglobulin heavy constant epsilon

Background

IgE is typically the least abundant isotype - blood serum IgE levels in a normal ("non-atopic") individual are ~150 ng/ml, compared to 10 mg/ml for the IgGs - it is capable of triggering the most powerful immune reactions. Most of our knowledge of IgE has come from research into the mechanism of a form of allergy known as type 1 hypersensitivity. There is much speculation into what physiological benefits IgE contributes, and so far, circumstantial evidence in animal models and statistical population trends have hinted that IgE may be beneficial in fighting gut parasites such as Schistosoma mansoni, but this has not been conclusively proven in humans. IgE may play an important role in the immune system's recognition of cancer, in which the stimulation of a strong cytotoxic response against cells displaying only small amounts of early cancer markers would be beneficial. IgE may be an important target in treatments for allergy and asthma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for IgE ELISA Kit (KA1944)(3)

Publications using KA1944

• Johnathan M, Gan SH, Ezumi MF et al. Phytochemical profiles and inhibitory effects of Tiger Milk mushroom (Lignosus rhinocerus) extract on ovalbumin-induced airway inflammation in a rodent model of asthma. BMC Complement Altern Med 2016-06-03 [PMID: 27255587]
• Seo JH, Bang MA, Kim G et al. Erythronium japonicum attenuates histopathological lung abnormalities in a mouse model of ovalbumin-induced asthma. Int J Mol Med 2016-05-01 [PMID: 27035741]
• Hussain Z, Katas H, Mohd Amin MC, Kumolosasi E Efficient immuno-modulation of TH1/TH2 biomarkers in 2,4-dinitrofluorobenzene-induced atopic dermatitis: nanocarrier-mediated transcutaneous co-delivery of anti-inflammatory and antioxidant drugs. PLoS One 2014-11-14 [PMID: 25396426] (ELISA)

Bioinformatics

• Gene Symbol: IGHE