MgcRacGAP/RACGAP1 Antibody [Unconjugated]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Chicken
• Conjugate: Unconjugated
• Concentration: LYOPH

MgcRacGAP/RACGAP1 Antibody [Unconjugated] Summary

• Immunogen: E. coli-derived recombinant human MgcRacGAP
  Met1-Lys632 (Lys518Ser)
  Accession # Q9H0H5
• Specificity: Detects human MgcRacGAP in direct ELISAs and Western blots.
• Source: N/A
• Isotype: IgY
• Clonality: Polyclonal
• Host: Chicken
• Gene: RACGAP1
• Purity Statement: Antigen Affinity-purified from egg yolks

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for MgcRacGAP/RACGAP1 Antibody [Unconjugated]

• GTPase activating protein
• HsCYK-4
• ID-GAP
• KIAA1478
• Male germ cell RacGap
• MgcRacGAP
• MgcRacGAPrac GTPase-activating protein 1
• Rac GTPase activating protein 1
• RACGAP1

Background

McgRac GAP is functionally converted to a Rho GAP via phosphorylation. The Rho GAP activity of MgcRac GAP has been shown to play essential roles in cytokinesis (1).

1. Hiroshima, Y. et al. (2003) Develop. Cell 4:549.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for MgcRacGAP/RACGAP1 Antibody (AF1424)(1)

Publication using AF1424

• Huang H, Fletcher L, Beeharry N, Daniel R, Kao G, Yen TJ, Muschel RJ Abnormal cytokinesis after X-irradiation in tumor cells that override the G2 DNA damage checkpoint. Cancer Res., 2008-05-15;68(10):3724-32. 2008-05-15 [PMID: 18483255] (ICC, Human)

Bioinformatics

• Gene Symbol: RACGAP1
• Uniprot:
  • Q9H0H5()