MOR-1C Antibody

Immunohistochemistry: MOR-1C Antibody [NB110-59977] - A-D-Staining of Differentiated Stem Cells. D3 ES cells were maintained in serum/LIF/ME induced self-renewal conditions (undifferentiated cells, D3). Upon treatment with 1 uM RA they undergo differentiation (dD3). Cells were fixed and permeabilized. Treatm

Product Discontinued

MOR-1C Antibody Summary

• Immunogen: KSCMDRGMRNLLPDDGPRQE
• Specificity: MOR-1C
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

This antibody is reactive against mouse and rat.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Whole serum
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Alternate Names for MOR-1C Antibody

• mu 1
• mu opioid receptor mor1o; mor1; mu opiate receptor; kiaa0403; opioid receptor mu 1; mu opioid receptor; oprm; mutype opioid receptor; opioid receptor

Background

Three types of opioid receptors have been cloned -- mu, delta, and kappa. Opioid receptors are seven transmembrane G-protein coupled receptors. They share a high degree of homology and are most divergent at the N- and C-termini. Activation of mu opioid receptors leads to a decrease in neuronal excitability. Several C-terminal splice variants have been identified for the Mu Opioid Receptor (MOR1) including MOR1C. These splice variants appear to differ in their pharmacological selectivity as well as their membrane trafficking.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Entrez:
  • 18390(Mouse)
  • 25601(Rat)