Mouse CD3+ T Cell, Mini Column Enrichment Kit

Mouse CD3+ T Cell, Mini Column [MTCC-525-NOV] - Mouse CD3+ T Cell, Mini Column Enrichment Kit

Product Discontinued

Mouse CD3+ T Cell, Mini Column Enrichment Kit Summary

• Description: Mouse T Cell Enrichment Columns are designed to prepare purified mouse T cell populations via high affinity negative selection. The resulting column eluate is a highly enriched T cell population with minimal depletion of T cell constituents.
  
  Features
  • Available for human, mouse, and rat cells
  • Purifies CD3+ T cells to 83 - 90%
  • Based upon gravitational flow
  • Simple procedure
  • No specialized equipment required
• Kit Type: Enrichment Kit
• Gene: CD3E

Applications/Dilutions

• Dilutions:
  • Flow Cytometry

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.

Background

The T cell receptor (TCR)/CD3 complex consists of two variable antigen-recognition receptor chains (TCR-alpha/TCR-beta or TCR-gamma/TCR-delta) that are non-covalently linked to at least four different invariant chains: CD3 gamma, CD3 delta, CD3 epsilon, and the CD3 zeta chain that exists as either a homodimer or as a heterodimer with its splice-variant the CD3 eta chain. The CD3 complex functions to transduce intracellular signals during TCR antigen recognition. CD3 is expressed early in thymocyte development, and on a subset of NK cells. CD3 epsilon is one of at least three invariant proteins that associate with the variable antigen recognition chains of the T cell receptor and function in signal transduction.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: CD3E