Nectin-4/PVRL4 Antibody (6D3) - BSA Free

ELISA: Nectin-4/PVRL4 Antibody (6D3) [NBP3-26115] - The Binding Activity of Nectin-4/PVRL4 with Nectin-4/PVRL4 Antibody. Activity: Measured by its binding ability in a functional ELISA. Immobilized Human Nectin-4/PVRL4 at 2 ug/mL can bind Nectin-4/PVRL4 Antibody, the EC50 is 0.6029-0.7837 ng/mL.

• Reactivity: Hu
• Applications: ELISA
• Clone: 6D3
• Clonality: Monoclonal
• Host: Human
• Conjugate: Unconjugated
• Format: BSA Free

Nectin-4/PVRL4 Antibody (6D3) - BSA Free Summary

• Additional Information: Recombinant monoclonal antibody expressed in HEK293F cells
• Immunogen: Recombinant Human Nectin-4/PVRL4 protein [UniProt Q96NY8]
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Gene: NECTIN4
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Store at -20 to -70C. Avoid freeze-thaw cycles.
• Buffer: 50% Glycerol, 0.01M PBS, PH 7.4
• Preservative: 0.03% Proclin 300
• Purity: Affinity purified

Alternate Names for Nectin-4/PVRL4 Antibody (6D3) - BSA Free

• EDSS1
• Ig superfamily receptor LNIR
• LNIR
• LNIRnectin 4
• Nectin4
• Nectin-4
• poliovirus receptor-related 4
• poliovirus receptor-related protein 4
• PRR4
• PRR4DKFZp686K05193
• PVRL4

Background

PVRL4, also known as Poliovirus receptor-related protein 4, is a 510 amino acid protein that is 55 kDa, predominantly expressed in placenta and breast carcinoma, is a single-pass type I membrane protein involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with PVRL2/nectin-1, and oes not act as receptor for alpha-herpesvirus entry into cells. Disease research is being performed in relation to this protein and ectodermal dysplasia, syndactyly, ectodermal dysplasia-syndactyly syndrome 1, measles, ovarian cancer, breast carcinoma, lung cancer, and carcinoma. The PVRL4 protein has shown an interaction with PVRL1, MLLT4, PICK1, TIGIT, PARD3, PVRL3, and PVRL2 in Adherens junctions interactions, Nectin/Necl trans heterodimerization, Cell junction organization, Cell-Cell communication, Cell-cell junction organization, Sertoli-Sertoli Cell Junction Dynamics, and Epithelial Adherens Junctions pathways.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NECTIN4