Human Noggin ELISA Kit (Colorimetric)

ELISA: Human Noggin ELISA Kit (Colorimetric) [NBP2-80296] - Samples were spiked with high concentrations of Human Noggin and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

ELISA: Human Noggin ELISA Kit (Colorimetric) [NBP2-80296] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma and other biological fluids
• Standard Curve Range: 125-8000 pg/mL
• Sensitivity: 75 pg/mL

Human Noggin ELISA Kit (Colorimetric) Summary

• Specificity: This kit recognizes Human NOG in samples. No significant cross-reactivity or interference between Human NOG and analogues was observed.
• Standard Curve Range: 125-8000 pg/mL
• Sensitivity: 75 pg/mL
• Assay Type: Sandwich-ELISA
• Inter-Assay: CV% < 4.96%
• Intra-Assay: CV% < 5.37%
• Spike Recovery: 85-104%
• Sample Volume: 100 ul
• Kit Type: ELISA Kit (Colorimetric)
• Gene: NOG

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human Noggin ELISA Kit (Colorimetric)

• NOG
• Noggin
• SYM1
• symphalangism 1 (proximal)
• synostoses (multiple) syndrome 1
• SYNS1
• SYNS1A

Background

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: NOG
• Uniprot:
  • Q13253()
  • Q13253()