Npas4 Antibody

Immunohistochemistry: Npas4 Antibody [NBP1-88616] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neuronal cells.

Product Discontinued

Npas4 Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: YLTFPSGPEPSLQAELSKDLVCTPPYTPHQPGGCAFLFSLHEPFQTHLPTPSSTLQEQLTPSTATFSDQLTPSSATFPDPLTSPLQGQLTETS
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NPAS4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%), Rat (89%)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Npas4 Antibody

• BHLHE79
• bHLHe79neuronal PAS domain-containing protein 4
• Class E basic helix-loop-helix protein 79
• Le-PAS
• neuronal PAS domain protein 4
• Neuronal PAS4
• NXFHLH-PAS transcription factor NXF
• PASD10PAS domain-containing protein 10

Background

Npas4 acts as a transcriptional activator in the presence of ARNT. It can activate the CME (CNS midline enhancer) element and the expression of the drebrin gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NPAS4