OSR1 Antibody (3F3)

Product Discontinued

OSR1 Antibody (3F3) Summary

• Immunogen: OSR1 (NP_660303, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag.MGSKTLPAPVPIHPSLQLTNYSFLQAVNGLPTVPSDHLPNLYGFSALHAVHLHQWTLGYPAMHLPRSSFSKVPGTVSSLVDARFQLPAFPWFPHVIQPKP
• Specificity: odd-skipped related 1 (Drosophila)
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: OSR1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Antibody reactive against recombinant protein on ELISA. It has also been used for immunohistochemistry on paraffin sections.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for OSR1 Antibody (3F3)

• ODDodd-skipped (Drosophila) homolog
• odd-skipped homolog
• odd-skipped related 1 (Drosophila)
• protein odd-skipped-related 1

Background

OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses. It may have a role in regulating the actin cytoskeleton.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for OSR1 Antibody (H00130497-M04)(5)

Publications using H00130497-M04

• Musah S, Dimitrakakis N, Camacho DM et al. Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip. Nat Protoc. 2018-07-01 [PMID: 29995874] (Human)
• Musah S, Mammoto A, Ferrante TC et al. Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip Nat Biomed Eng. 2017-05-10 [PMID: 29038743] (ICC/IF, Human)
• Xia Y, Sancho-Martinez I, Nivet E et al. The generation of kidney organoids by differentiation of human pluripotent cells to ureteric bud progenitor-like cells. Nat Protoc. 2014-10-23 [PMID: 25340442]
• Xia Y, Nivet E, Sancho-Martinez I et al. Directed differentiation of human pluripotent cells to ureteric bud kidney progenitor-like cells. Nat Cell Biol. 2013-11-17 [PMID: 24240476]
• Yang SS, Lo YF, Wu CC et al. SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction. J Am Soc Nephrol 21(11):1868-77. 2010-11-01 [PMID: 20813865]

Bioinformatics

• Gene Symbol: OSR1
• Entrez:
  • 130497(Human)
• OMIM:
  • 608891(Human)
• Uniprot:
  • NP_660303(Human)