PIP2 Antibody (PIP2 2C11) [DyLight 550]

Product Discontinued

PIP2 Antibody (PIP2 2C11) [DyLight 550] Summary

• Immunogen: Liposomes (prepared in PBS with lipid A, phosphatidylcholine (PC) and cholesterol) containing synthetic di-palmitoyl PtdIns(4,5)P2.
• Specificity: Cross reacts with PtdIns(4,5)P2, Ptd(4)P and Ptd(3,4,5)P3.
• Isotype: IgM
• Clonality: Monoclonal
• Host: Mouse
• Purity: Chromatography

Applications/Dilutions

• Dilutions:
  • Chromatin Immunoprecipitation (ChIP)
  • Dot Blot
  • ELISA
  • Functional
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunoprecipitation
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Chromatography

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PIP2 Antibody (PIP2 2C11) [DyLight 550]

• 1,2-Diacyl-sn-glycero-3-phospho-(1-D-myo-inositol 4,5-bisphosphate)
• Phosphatidylinositol 4,5-bisphosphate
• Phosphatidylinositol biphosphate
• Phosphatidylinositol diphosphate
• PIP 2

Background

Phosphatidylinositol 4,5-biphosphate (PIP2) is a membrane phospholipid that has been implicated in a variety of cellular processes, including synaptic vesicle recycling and signal transduction pathways. PLCD4 hydrolyzes PIP2 to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.