RBPMS Antibody

ELISA: RBPMS Antibody [NBP2-80389] - Coating Antigens: free peptide Coating Concentration: 2 ug/ml, 100ul / wellCoating Buffer: Phosphate Buffered Saline, pH7.4 Secondary Antibody: Goat Anti-Guinea pig IgG (H+L), HRP Conjugated(1:1000)

• Reactivity: Hu, Mu
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Guinea Pig
• Conjugate: Unconjugated
• Concentration: 1 mg/ml

RBPMS Antibody Summary

• Immunogen: Synthetic peptide within human RBPMS 1-30 conjugated to Keyhole Limpet Haemocyanin. (SwissProt: Q93062 Human; SwissProt: Q9WVB0 Mouse)
• Localization: Cytoplasm. Nucleus.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Guinea Pig
• Gene: RBPMS
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:1000-1:5000
  • Western Blot 1:500-1:1000
• Theoretical MW: 21 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH7.4), 0.2% BSA, 50% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for RBPMS Antibody

• FLJ32971
• Heart and RRM expressed sequence
• HERMES
• HERMESRNA-binding protein with multiple splicing
• RBPMS
• RBP-MS
• RNA binding protein with multiple splicing

Background

Encoded by a member of the RRM family of RNA-binding proteins, RBPMS is involved in nucleic acid, nucleotide, RNA and protein binding. The RRM family can be found between 80-100 amino acids in length. RBPMS also acts as a coactivator of transcriptional activity and is required for TGFB1/Smad-mediated transactivation. More specifically, RBPMS acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity while promoting the nuclear accumulation of these proteins. Diseases associated with RBPMS include hepatocellular carcinoma, ataxia, carcinoma and neuronitis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RBPMS