SIK1/Snf1lk Antibody (2C12) - Azide and BSA Free

Immunocytochemistry/Immunofluorescence: SIK1/Snf1lk Antibody (2C12) [H00150094-M01] - Analysis of monoclonal antibody to SIK1 on HeLa cell . Antibody concentration 10 ug/ml.

Immunohistochemistry-Paraffin: SIK1/Snf1lk Antibody (2C12) [H00150094-M01] - Analysis of monoclonal antibody to SIK1 on formalin-fixed paraffin-embedded human placenta. Antibody concentration 3 ug/ml.

ELISA: SIK1/Snf1lk Antibody (2C12) [H00150094-M01] - Detection limit for recombinant GST tagged SIK1 is 0.3 ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: ELISA, ICC/IF, IHC
• Clone: 2C12
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

SIK1/Snf1lk Antibody (2C12) - Azide and BSA Free Summary

• Immunogen: SIK1 (AAH38504.1, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHIIKLYQVMETKDMLY
• Specificity: Reacts with salt-inducible kinase 1.
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: SIK1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: This antibody is reactive against recombinant protein in ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for SIK1/Snf1lk Antibody (2C12) - Azide and BSA Free

• EC 2.7.11
• EC 2.7.11.1
• msk
• myocardial SNF1-like kinase
• salt-inducible kinase 1
• Salt-inducible protein kinase 1
• serine/threonine protein kinase
• serine/threonine-protein kinase SIK1
• Serine/threonine-protein kinase SNF1-like kinase 1
• Serine/threonine-protein kinase SNF1LK
• SIK
• SIK1
• SIK-1
• SIK1/Snf1lk
• SNF1-like kinase
• SNF1LK
• SNF1LKMSK

Background

Transient role during the earliest stages of myocardial cell differentiation and/or primitive chamberformation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation.Potential role in G2/M cell cycle regulation. Inhibits CREB activity by phosphorylating and repressing theCREB-specific coactivators, CRTC1-3

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SIK1/Snf1lk Antibody (H00150094-M01)(1)

Publication using H00150094-M01

• Hansen J, Snow C, Tuttle E et al. De Novo Mutations in SIK1 Cause a Spectrum of Developmental Epilepsies. Am J Hum Genet. 2015-04-02 [PMID: 25839329]

Bioinformatics

• Gene Symbol: SIK1
• Entrez:
  • 150094(Human)
• Uniprot:
  • AAH38504(Human)