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Eukaryotic cellular components are organized into membrane-bound compartments called organelles. These structurally complex compartments serve specific biological roles and are crucial for proper cellular function. For example, mitochondria carry out cellular respiration, while lysosomes function in cellular digestion to break down biomolecules. The specialized function of each organelle is determined by the unique proteins they contain. Organelle-specific proteins can function as markers to identify organelles in cell biology immunoassays, as well as act as a tool to explore the subcellular localization of novel proteins. By immunostaining for the protein of interest along with an organelle marker, their co-localization confirms the subcellular localization of the target protein. In addition, organelle markers can be used in Western blot analysis to confirm the purity of various fractions in experiments involving cellular fractionation.
Organelle Marker AntibodiesNovus Biologicals offers extensively validated high quality antibodies for various markers. Our most popular antibodies for organelle markers are:
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Request a print copy of our Organelle Markers brochure
Download our Organelle Markers brochure
