Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Species: Rt
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. [provided by RefSeq]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
210 |
| Alternate Names |
- ALADHEC 4.2.1.24
- aminolevulinate dehydratase
- aminolevulinate, delta-, dehydratase
- delta-aminolevulinic acid dehydratase
- PBGSMGC5057
- Porphobilinogen synthase
|
