Human beta-Arrestin 1 ELISA Kit (Colorimetric)

ELISA: Human beta-Arrestin 1 ELISA Kit (Colorimetric) [NBP2-69864] - Samples were spiked with high concentrations of Human beta-Arrestin 1 and diluted with Reference Standard & Sample Diluent to produce samples with values within the range of the assay.

ELISA: Human beta-Arrestin 1 ELISA Kit (Colorimetric) [NBP2-69864] - Standard Curve Reference

• Reactivity: Hu
• Applications: ELISA
• Suitable Sample Type: Serum, plasma and other biological fluids
• Standard Curve Range: 62.50 - 4000 pg/mL
• Sensitivity: 37.50 pg/mL

Human beta-Arrestin 1 ELISA Kit (Colorimetric) Summary

• Specificity: This kit recognizes Human ARR(beta)1 in samples. No significant cross-reactivity or interference between Human ARR(beta)1 and analogues was observed.
• Standard Curve Range: 62.50 - 4000 pg/mL
• Sensitivity: 37.50 pg/mL
• Assay Type: Sandwich-ELISA
• Inter-Assay: CV% < 4.76%
• Intra-Assay: CV% < 4.88%
• Spike Recovery: 89-106%
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: ARRB1

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human beta-Arrestin 1 ELISA Kit (Colorimetric)

• ARB1
• ARR1
• ARRB1
• arrestin 2
• Arrestin beta-1
• arrestin, beta 1
• betaArrestin 1
• beta-Arrestin 1
• beta-arrestin-1

Background

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization ofG-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones,neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in thebeta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the centralnervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin systemis believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcriptsencoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known.(provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: ARRB1