Home » BTLA/CD272 » BTLA/CD272 Antibodies » BTLA/CD272 Antibody - Humanized, IgG4SP, (Research Grade icatolimab Biosimilar) - Low Endotoxin, Azide and BSA Free

BTLA/CD272 Antibody - Humanized, IgG4SP, (Research Grade icatolimab Biosimilar) - Low Endotoxin, Azide and BSA Free

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Immobilized human BTLA His at 2 ug/mL can bind BTLA/CD272 Antibody (icatolimab) - Humanized, IgG4SP, EC50=0.01515 ug/mL.
Immobilized human BTLA His at 2 ug/mL can bind BTLA/CD272 Antibody (icatolimab) - Humanized, IgG4SP, EC50=0.01515 ug/mL.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, Func
Clonality
Monoclonal
Host
Human
Conjugate
Unconjugated
Format
Low Endotoxin, Azide and BSA Free
Concentration
LYOPH

Order Details

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View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-28499AF350
Alexa Fluor 405
NBP3-28499AF405
Alexa Fluor 488
NBP3-28499AF488
Alexa Fluor 532
NBP3-28499AF532
Alexa Fluor 594
NBP3-28499AF594
Alexa Fluor 647
NBP3-28499AF647
Alexa Fluor 700
NBP3-28499AF700
Alexa Fluor 750
NBP3-28499AF750
Allophycocyanin
NBP3-28499APC
Biotin
NBP3-28499B
CoraFluor 1
NBP3-28499CL1
DyLight 350
NBP3-28499UV
DyLight 405
NBP3-28499V
DyLight 488
NBP3-28499G
DyLight 550
NBP3-28499R
DyLight 594
NBP3-28499DL594
DyLight 650
NBP3-28499C
DyLight 680
NBP3-28499FR
DyLight 755
NBP3-28499IR
FITC
NBP3-28499F
HRP
NBP3-28499H
Janelia Fluor 525
NBP3-28499JF525
Janelia Fluor 549
NBP3-28499JF549
Janelia Fluor 646
NBP3-28499JF646
Janelia Fluor 669
NBP3-28499JF669
PE
NBP3-28499PE
PerCP
NBP3-28499PCP
mFluor Violet 450 SE
NBP3-28499MFV450
mFluor Violet 500 SE
NBP3-28499MFV500
mFluor Violet 610 SE
NBP3-28499MFV610
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BTLA/CD272 Antibody - Humanized, IgG4SP, (Research Grade icatolimab Biosimilar) - Low Endotoxin, Azide and BSA Free Summary

Description
Expressed from CHO. The heavy chain type is huIgG4SP, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Also known as 'icatolimab'.

IgG4SP is human IgG4 with S228P mutation.

This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
Additional Information
Recombinant Monoclonal Antibody
Immunogen
BTLA / CD272
Isotype
IgG4
Clonality
Monoclonal
Host
Human
Gene
BTLA
Purity
Protein A purified
Endotoxin Note
< 0.001EU/ug,determined by LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

Storage
Store at -20C in powder form. Store at -80C once reconstituted.
Buffer
Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for Array

  • B and T lymphocyte associated
  • B and T lymphocyte attenuator
  • B- and T-lymphocyte attenuator
  • B- and T-lymphocyte-associated protein
  • BTLA
  • BTLA1
  • CD272 antigen
  • CD272
  • FLJ16065
  • MGC129743

Background

BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 (MIM 600244) and CTLA4 (MIM 123890), BTLA interacts with a B7 homolog, B7H4.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol BTLA
Uniprot