Monkey C-Reactive Protein/CRP ELISA Kit (Colorimetric)

Monkey C-Reactive Protein/CRP ELISA Kit (Colorimetric) [NBP3-23449] - Standard Curve Reference

• Reactivity: Pm
• Applications: ELISA
• Suitable Sample Type: Serum, plasma, cell culture supernates and tissue homogenates
• Standard Curve Range: 0.625 ng/mL - 40 ng/mL
• Sensitivity: 0.156 ng/mL

Monkey C-Reactive Protein/CRP ELISA Kit (Colorimetric) Summary

• Description: Assay Length: 1-5 hours
• Specificity: This assay has high sensitivity and excellent specificity for detection of monkey C-Reactive Protein/CRP. No significant cross-reactivity or interference between monkey C-Reactive Protein/CRP and analogues was observed.
• Standard Curve Range: 0.625 ng/mL - 40 ng/mL
• Sensitivity: 0.156 ng/mL
• Assay Type: Sandwich ELISA
• Inter-Assay: %CV < 10
• Intra-Assay: %CV < 8
• Sample Volume: 50 - 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: CRP

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Monkey C-Reactive Protein/CRP ELISA Kit (Colorimetric)

• C-Reactive Protein
• C-reactive protein, pentraxin-related
• CRP
• MGC88244
• pentraxin 1
• PTX1MGC149895

Background

C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: CRP