CCL25/TECK Antibody - Azide and BSA Free

Immunohistochemistry-Paraffin: CCL25/TECK Antibody [NBP1-40993] - Normal human small bowel.

Immunohistochemistry-Paraffin: CCL25/TECK Antibody [NBP1-40993] - Normal human small bowel.

• Reactivity: Hu
• Applications: WB, ELISA, Func, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: 1.0 mg/ml

CCL25/TECK Antibody - Azide and BSA Free Summary

• Immunogen: Recombinant human CCL25
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CCL25
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA 0.5-2 ug/ml
  • Functional 10.0-15 ug/ml
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 0.5-1.0 ug/ml
  • Western Blot 0.1-0.2 ug/ml
• Application Notes: For IHC-P: This product requires protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: 1.0 mg/ml
• Purity: IgG purified

Alternate Names for CCL25/TECK Antibody - Azide and BSA Free

• C-C motif chemokine 25
• CCL25
• chemokine (C-C motif) ligand 25
• Chemokine TECK
• Ck beta-15
• Ckb15
• SCYA25TECKvar
• small inducible cytokine subfamily A (Cys-Cys), member 25
• Small-inducible cytokine A25
• TECK
• TECKMGC150327
• thymus expressed chemokine
• Thymus-expressed chemokine

Background

This gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for dendritic cells, thymocytes, and activated macrophages but is inactive on peripheral blood lymphocytes and neutrophils. The product of this gene binds to chemokine receptor CCR9. CCL25, otherwise known as TECK (thymus expressed chemokine), a member of the intercrine beta (chemokine CC) family, specifically expressed by thymic stromal cells, which acts as a chemotactic factor for activated macrophages, thymocytes and dendritic cells, and signals through binding to the CCR9 receptor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CCL25/TECK Antibody (NBP1-40993)(1)

Publication using NBP1-40993

• Egan CE, Sodhi CP, Good M et al. Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis. J. Clin. Invest. 2015-12-21 [PMID: 26690704] (IHC-P, Mouse)

Bioinformatics

• Gene Symbol: CCL25
• Entrez:
  • 6370(Human)
• Uniprot:
  • O15444()
  • O15444()