csl/RBPJK Antibody (JB49-34)

Western Blot: csl/RBPJK Antibody (JB49-34) [NBP2-75452] - Analysis of RBPJK on human colon tissue lysates using anti-RBPJK antibody at 1/500 dilution.

Product Discontinued

csl/RBPJK Antibody (JB49-34) Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Recombinant protein within Human csl/RBPJK aa 81-184 / 500. (SwissProt: Q06330 Human)
• Localization: Cytoplasm. Nucleus.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: RBPJ
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000-1:5000
• Theoretical MW: 55 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: TBS (pH7.4), 0.05% BSA, 40% Glycerol
• Preservative: 0.05% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for csl/RBPJK Antibody (JB49-34)

• CBF1
• CBF-1
• CSL
• H-2K binding factor-2
• IGKJRB1
• IGKJRB1RBPSUHCBF1
• IGKJRBRBP-J kappa
• immunoglobulin kappa J region recombination signal binding protein 1
• J kappa-recombination signal-binding protein
• KBF2
• RBPJ
• RBP-JK
• RBPJKMGC61669
• RBP-Jrecombining binding protein suppressor of hairless (Drosophila)
• RBPSUH
• recombination signal binding protein for immunoglobulin kappa J region
• recombining binding protein suppressor of hairless
• Renal carcinoma antigen NY-REN-30
• SUH
• suppressor of hairless homolog

Background

Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RBPJ