FANCI Antibody - BSA Free

Images

 
Immunohistochemistry-Paraffin: FANCI Antibody [NBP1-84608] - Staining of human cerebral cortex shows strong nuclear positivity in neurons.
Orthogonal Strategies: Immunohistochemistry-Paraffin: FANCI Antibody [NBP1-84608] - Analysis in human testis and liver tissues using NBP1-84608 antibody. Corresponding FANCI RNA-seq data are presented for the ...read more
Immunohistochemistry-Paraffin: FANCI Antibody [NBP1-84608] - Staining of human testis shows strong nuclear positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: FANCI Antibody [NBP1-84608] - Staining of human Rectum shows strong nuclear positivity in glandular cells.
Immunohistochemistry-Paraffin: FANCI Antibody [NBP1-84608] - Staining of human liver shows no positivity in hepatocytes as expected.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Validated by:
       

Orthogonal Strategies

 

Order Details

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Catalog# & Formulation Size Price

FANCI Antibody - BSA Free Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: YGKGVLSGEECKKQLINTLCSGRWDQQYVIQLTSMFKDVPLTAEEVEFVVEKALSMFSKMNLQEIPPLVYQLLVLSSKGSRKSVLEGIIAFFSALDKQHNEEQSGDELLDVVTVPSGE
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FANCI
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:500 - 1:1000
  • Immunohistochemistry-Paraffin 1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
FANCI Protein (NBP1-84608PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for FANCI Antibody - BSA Free

  • Fanconi anemia group I protein
  • Fanconi anemia, complementation group I
  • KIAA1794FLJ10719
  • Protein FACI

Background

FANCI is the gene underlying Fanconi anemia complementation group I, a syndrome characterized by a predisposition to cancer, congenital malformations, and pancytopenia. At the cellular level, FANCI is involved in the S and G2 phase DNA damage checkpoint and in the repair of DNA double-strand breaks and cross-links.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional FANCI Products

Array NBP1-84608

Research Areas for FANCI Antibody (NBP1-84608)

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Blogs on FANCI.

FANCD2 and DNA damage repair
Fanconi anemia (FA) is a genetically inherited disorder that yields cytogenetic instability, hypersensitivity to DNA crosslinking compounds and defective DNA repair. A variety of genes have been identified within the FA pathway that are referred t...  Read full blog post.

Fanconi Antibodies and Cancer Research
We at Novus Biologicals have an extensive antibody databasedevoted to the 13 Fanconi anaemia complementation (FANC) genes, which are involved in the recognition and repair of damaged DNA.The core complex of 8 proteins (FANCA, B, C, E, F, G, L and M)...  Read full blog post.

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Bioinformatics

Gene Symbol FANCI