GABA-AR alpha 6 Antibody - BSA Free

Western Blot: GABA-AR alpha 6 Antibody [NBP3-12973] - Human tissue extract (30 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with GABA-AR alpha 6 antibody (NBP3-12973) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.

Western Blot: GABA-AR alpha 6 Antibody [NBP3-12973] - Rat tissue extract (50 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with GABRA6 antibody (NBP3-12973) diluted at 1:1000.

Western Blot: GABA-AR alpha 6 Antibody [NBP3-12973] - Mouse tissue extract (50 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with GABRA6 antibody (NBP3-12973) diluted at 1:1000.

Immunohistochemistry-Paraffin-GABA-AR alpha 6 Antibody-NBP3-12973-Rat brain.GABA A Receptor alpha 6 stained by GABA A Receptor alpha 6 antibody diluted at 1:500.Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

GABA-AR alpha 6 Antibody - BSA Free Summary

• Description: Centrifuge briefly prior to opening.
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human GABA-AR alpha 6. The exact sequence is proprietary.
• Predicted Species: Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GABRA6
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry Assay dependent
  • Immunohistochemistry-Paraffin Assay dependent
  • Western Blot 1:500-1:3000
• Theoretical MW: 51 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol
• Preservative: 0.025% Proclin 300
• Purity: Antigen Affinity-purified

Alternate Names for GABA-AR alpha 6 Antibody - BSA Free

• GABA A R alpha 6
• GABA subunit A receptor alpha 6
• GABA(A) receptor subunit alpha-6
• GABAAR alpha 6
• GABAARa6
• GABRA6
• gamma-aminobutyric acid (GABA) A receptor, alpha 6
• gamma-aminobutyric acid receptor subunit alpha-6
• MGC116903
• MGC116904

Background

GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA (A) Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics. The alpha 6 subunit is expressed in cerebellar granule cells. Though it is concentrated at synapses, it is found on extrasynaptic membranes, as well.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GABRA6