Human GLP1 ELISA Kit (Colorimetric)

ELISA: Human GLP1 ELISA Kit (Colorimetric) [NBP2-82126] - Standard Curve Reference

Product Discontinued

Human GLP1 ELISA Kit (Colorimetric) Summary

• Specificity: This kit recognizes Human GLP1 in samples. No Significant cross-reactivity or interference between Human GLP1 and analogues was observed
• Standard Curve Range: 0.31 - 20 ng/mL
• Sensitivity: 0.19 ng/mL
• Assay Type: Sandwich-ELISA
• Inter-Assay: CV% < 6%
• Intra-Assay: CV% < 6%
• Spike Recovery: average = 101% for serum; average = 92% for EDTA plasma; average = 93% for cell culture media
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: GCG

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Storage of components varies. See protocol for specific instructions.

Alternate Names for Human GLP1 ELISA Kit (Colorimetric)

• glicentin-related polypeptide
• GLP1
• GLP-1
• glucagon-like peptide 1
• GRPP

Background

Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and glucagon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogenesis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for GLP1 ELISA Kit (NBP2-82126)(2)

Publications using NBP2-82126

• Fan D, Wang Y, Liu B, Yin F Hypoglycemic drug liraglutide alleviates low muscle mass by inhibiting the expression of MuRF1 and MAFbx in diabetic muscle atrophy Journal of the Chinese Medical Association : JCMA 2022-10-24 [PMID: 36279106]
• Tuccinardi D, Di Mauro A, Lattanzi G Et al. An Extra Virgin Olive Oil-enriched Chocolate Spread Positively Modulates Insulin-Resistance Markers compared With a Palm Oil-enriched one in Healthy Young Adults: A Double-Blind, Cross-Over, Randomized Controlled Trial Diabetes/metabolism research and reviews 2021-08-25 [PMID: 34435429] (ELISA)

Bioinformatics

• Gene Symbol: GCG