Human IL-8/CXCL8 DuoSet ELISA, 15 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human IL-8/CXCL8 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: CXCL8

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IL-8/CXCL8 DuoSet ELISA, 15 Plate

• 3-10C
• AMCF-I
• C-X-C motif chemokine 8
• CXCL8
• CXCL8SCYB8
• Emoctakin
• GCP1
• GCP-1TSG-1
• IL8
• IL-8
• interleukin 8
• K60
• LAI
• LECT
• LUCT
• LYNAP
• MDNCF
• MDNCFb-ENAP
• member 8
• MONAP
• MONAPGCP1
• NAF
• NAP1
• NAP-1NAP1
• NCF
• Neutrophil-activating protein 1
• Protein 3-10C
• T cell chemotactic factor
• T-cell chemotactic factor
• TCF
• TSG1

Background

Interleukin-8 (IL-8), also known as IL-8, GCP-1, and NAP-1, is a heparin-binding 8-9 kDa member of the alpha, or CXC family of chemokines. There are at least 15 human CXC family members that all adopt a three beta -sheet/one alpha -helix structure. Most CXC chemokines show an N-terminal Glu-Leu-Arg (ELR) tripeptide motif. IL-8 circulates as a monomer, homodimer, and heterodimer with CXCL4/PF4. The monomer is considered the most bio-active, while the heterodimer can potentiate PF4 activity. IL-8 oligomerization is modulated by its interactions with matrix and cell surface glycosaminoglycans (GAGs). Mature human IL-8 shares 65-69% amino acid (aa) identity with canine, feline, and porcine IL-8. There is no IL-8 gene counterpart in rodent. 

Multiple isoforms of IL-8 are generated through both alternative splicing and differential proteolytic cleavage. In humans, alternative splicing generates an iso-form with an eleven aa substitution at the C-terminus. Proteolytic processing results in N-terminal truncation of IL-8 and is likely a cell-specific event. For example, fibroblasts and endothelial cells generate the 1-77 form by cleaving IL-8 following Glu21, while monocytes and lymphocytes generate the 6-77 form by cleaving following Leu25. These truncated forms generally show increased bioactivity, particularly through the CXCR1 receptor. IL-8 can also undergo citrullination on Arg27 of the precursor, a modification that increases its half-life and ability to induce leukocytosis. A wide variety of cells secrete IL-8 including monocytes and neutrophils, fibroblasts and keratinocytes, mast cells, visceral smooth muscle cells, dendritic cells, type II great alveolar cells, and endothelial cells. 

IL-8 bioactivity is mediated through two G-protein-coupled receptors, termed CXCR1/IL-8 RA and CXCR2/IL-8 RB. CXCR1 is 45-50 kDa in size and is used almost exclusively by IL-8. CXCR2 is 35-40 kDa in size and is used by nearly all CXC chemokines. Both CXCR1 and CXCR2 constitutively associate into functional homodimers. They can also heterodimerize, but these complexes dissociate following IL-8 binding. CXCR2 responds to low concentrations of IL-8 and is principally associated with chemotaxis and MMP-9 release. CXCR1, in contrast, responds to high concentrations of IL-8 and is associated with respiratory burst and phospholipase D2 activation. Thus, CXCR2 ligation induces leukocyte adhesion to activated vascular endothelium and migration to sites of inflammation, while CXCR1 ligation primes neutrophil antimicrobial activity. IL-8 can also form a complex with Serpin A1/alpha-1 Antitrypsin, and this prevents IL-8 interaction with CXCR1. 

In addition to its pro-inflammatory effects, IL-8 is involved in angiogenesis and the pathogenesis of atherosclerosis and cancer. It induces VEGF expression in vascular endothelial cells and functions as an autocrine factor for EC growth and angiogenesis. It is upregulated in atherosclerotic lesions and is elevated in the serum and cerebrospinal fluid following myocardial infarction. In cancer, IL-8 promotes epithelial-mesenchymal transition as well as tumor cell invasiveness and metastasis.

Publications for CXCL8/IL-8 (DY208)(479)

Publications using DY208

• Somova, M;Simm, S;Ehrhardt, J;Schoon, J;Burchardt, M;Pinto, PC; SARS-CoV-2 Spike Protein Amplifies the Immunogenicity of Healthy Renal Epithelium in the Presence of Renal Cell Carcinoma Cells 2024-12-10 [PMID: 39768130] (ELISA, Human)
• Pourfarzam, S;Ardestani, SK;Jamali, T;Ghazanfari, H;Naghizadeh, MM;Faghihzadeh, S;Yaraee, R;Ghazanfari, Z;Ghazanfari, T; Distinct inflammatory profiles in mustard lung: A study of sulfur mustard-exposed patients with serious pulmonary complications International immunopharmacology 2024-12-16 [PMID: 39689604] (Human)
• Tucker, RM;Kim, N;Gurzell, E;Mathi, S;Chavva, S;Senthilkumar, D;Bartunek, O;Fenton, KC;Herndon-Fenton, SJ;Cardino, VN;Cooney, GM;Young, S;Fenton, JI; Commonly Used Dose of Montmorency Tart Cherry Powder Does Not Improve Sleep or Inflammation Outcomes in Individuals with Overweight or Obesity Nutrients 2024-11-28 [PMID: 39683518] (Human)
• Hanford, HE;Price, CTD;Uriarte, S;Abu Kwaik, Y; Inhibition and evasion of neutrophil microbicidal responses by Legionella longbeachae mBio 2024-12-16 [PMID: 39679679] (Human)
• Bekirian, C;Valsecchi, I;Bachellier-Bassi, S;Scandola, C;Guijarro, JI;Chauvel, M;Mourer, T;Gow, NAR;Aimanianda, VK;d'Enfert, C;Fontaine, T; ?-1,6-Glucan plays a central role in the structure and remodeling of the bilaminate fungal cell wall eLife 2024-12-05 [PMID: 39636210] (Human)
• Iaia, N;Canzoneri, F;Biasi, F;Poli, G;Menta, R;Testa, G;Gamba, P; The CaCo-2 cell junction derangement exerted by the single addition of oxysterols commonly detected in foods is markedly quenched when they are in mixture The Journal of steroid biochemistry and molecular biology 2024-11-27 [PMID: 39613194] (Human)
• Bousch, JF;Beyersdorf, C;Schultz, K;Windolf, J;Suschek, CV;Maus, U; Proinflammatory Cytokines Enhance the Mineralization, Proliferation, and Metabolic Activity of Primary Human Osteoblast-like Cells International journal of molecular sciences 2024-11-18 [PMID: 39596421] (Human)
• Snuggs, JW;Senter, RK;Whitt, JP;Jackson, JD;Le Maitre, CL; PCRX-201, a novel IL-1Ra gene therapy treatment approach for low back pain resulting from intervertebral disc degeneration Gene therapy 2024-11-21 [PMID: 39572769] (Human)
• Vargas-Castro, R;García-Quiroz, J;Olmos-Ortiz, A;Avila, E;Larrea, F;Díaz, L; Calcitriol prevents SARS-CoV spike-induced inflammation in human trophoblasts through downregulating ACE2 and TMPRSS2 expression The Journal of steroid biochemistry and molecular biology 2025-01-01 [PMID: 39515592] (Human)
• Sakwe, NI;Vuong, NB;Black, PJ;Ball, DD;Thomas, P;Beasley, HK;Hinton, A;Ochieng, J;Sakwe, AM; Annexin A6 modulates the secretion of pro-inflammatory cytokines and exosomes via interaction with SNAP23 in triple negative breast cancer cells bioRxiv : the preprint server for biology 2024-10-25 [PMID: 39484394] (Human)
• You, DJ;Gorman, BM;Goshi, N;Hum, NR;Sebastian, A;Kim, YH;Enright, HA;Buchholz, BA; Eucalyptus Wood Smoke Extract Elicits a Dose-Dependent Effect in Brain Endothelial Cells International journal of molecular sciences 2024-09-24 [PMID: 39408618] (Bioassay, Human)
• Karamanova, N;Morrow, KT;Maerivoet, A;Madine, J;Li, M;Migrino, RQ; Medin Induces Pro-Inflammatory Activation of Human Brain Vascular Smooth Muscle Cells bioRxiv : the preprint server for biology 2024-09-17 [PMID: 39345549] (Human)
• Zhu, W;Cremonini, E;Mastaloudis, A;Oteiza, PI; Glucoraphanin and sulforaphane mitigate TNF?-induced Caco-2 monolayers permeabilization and inflammation Redox biology 2024-09-17 [PMID: 39298837] (Human)
• Wang, L;Dos Santos Sanches, N;Panahipour, L;Imani, A;Yao, Y;Zhang, Y;Li, L;Gruber, R; Dimethyl Fumarate-Loaded Gellan Gum Hydrogels Can Reduce In Vitro Chemokine Expression in Oral Cells International journal of molecular sciences 2024-08-31 [PMID: 39273432] (Human)
• Hampton, TH;Barnaby, R;Roche, C;Nymon, A;Fukutani, KF;MacKenzie, TA;Stanton, BA; Gene expression responses of CF airway epithelial cells exposed to elexacaftor/tezacaftor/ivacaftor (ETI) suggest benefits beyond improved CFTR channel function bioRxiv : the preprint server for biology 2024-08-29 [PMID: 39257747] (Human)
• Maruthupandy, M;Jeon, JH;Noh, J;Yang, SI;Cho, WS; Mitigated toxicity of polystyrene nanoplastics in combination exposure with copper ions by transformation into copper (I) oxide: Inhibits the oxidative potential of nanoplastics Chemosphere 2024-09-05 [PMID: 39243901] (Human)
• Soko?owska, P;Wiktorowska-Owczarek, A;Tambor, J;Gawlak-Socka, S;Kowalczyk, E;Jó?wiak-B?benista, M; Endoplasmic Reticulum Stress Differently Modulates the Release of IL-6 and IL-8 Cytokines in Human Glial Cells International journal of molecular sciences 2024-08-09 [PMID: 39201378] (Human)
• Pedersen, BH;Simões, FB;Pogrebnyakov, I;Welch, M;Johansen, HK;Molin, S;La Rosa, R; Metabolic specialization drives reduced pathogenicity in Pseudomonas aeruginosa isolates from cystic fibrosis patients PLoS biology 2024-08-23 [PMID: 39178315] (Human)
• Cabrera, LE;Jokiranta, ST;Mäki, S;Miettinen, S;Kant, R;Kareinen, L;Sironen, T;Pietilä, JP;Kantele, A;Kekäläinen, E;Lindgren, H;Mattila, P;Kipar, A;Vapalahti, O;Strandin, T; The assembly of neutrophil inflammasomes during COVID-19 is mediated by type I interferons PLoS pathogens 2024-08-01 [PMID: 39172744] (Human)
• Zima, K;Khaidakov, B;Sochocka, M;Ochnik, M;Lemke, K;Kowalczyk, P; Exploring the potency of polyphenol-rich blend from Lonicera caerulea var. Kamtschatica sevast., Aronia melanocarpa, and Echinacea purpurea: Promising anti-inflammatory, antioxidant, and antiviral properties Heliyon 2024-08-15 [PMID: 39170264] (Human)
• Caohuy, H;Eidelman, O;Chen, T;Mungunsukh, O;Yang, Q;Walton, NI;Pollard, BS;Khanal, S;Hentschel, S;Florez, C;Herbert, AS;Pollard, HB; Inflammation in the COVID-19 airway is due to inhibition of CFTR signaling by the SARS-CoV-2 spike protein Scientific reports 2024-07-23 [PMID: 39043712] (Human)
• Nasr, MA;Aldous, A;Daniels, J;Joy, C;Capozzi, E;Yang, M;Moriarty, P;Emmanuel-Baker, V;Malcolm, S;Green, SJ;Gomez-Lobo, V;Ghosh, M; Effect of progestin-based contraceptives on HIV-associated vaginal immune biomarkers and microbiome in adolescent girls PloS one 2024-07-15 [PMID: 39008499] (Human)
• Haddad, MJ;Zuluaga-Arango, J;Mathieu, H;Barbezier, N;Anton, PM; Intestinal Epithelial Co-Culture Sensitivity to Pro-Inflammatory Stimuli and Polyphenols Is Medium-Independent International journal of molecular sciences 2024-07-04 [PMID: 39000465] (Human)
• Seo, DY;Park, JW;Kim, SH;Oh, SR;Han, SB;Kwon, OK;Ahn, KS; Effect of Isoscopoletin on Cytokine Expression in HaCaT Keratinocytes and RBL-2H3 Basophils: Preliminary Study International journal of molecular sciences 2024-06-24 [PMID: 39000019] (Human)
• Reedy, JL;Jensen, KN;Crossen, AJ;Basham, KJ;Ward, RA;Reardon, CM;Brown Harding, H;Hepworth, OW;Simaku, P;Kwaku, GN;Tone, K;Willment, JA;Reid, DM;Stappers, MHT;Brown, GD;Rajagopal, J;Vyas, JM; Fungal melanin suppresses airway epithelial chemokine secretion through blockade of calcium fluxing Nature communications 2024-07-10 [PMID: 38987270] (Human)
• Katsoulis, O;Toussaint, M;Jackson, MM;Mallia, P;Footitt, J;Mincham, KT;Meyer, GFM;Kebadze, T;Gilmour, A;Long, M;Aswani, AD;Snelgrove, RJ;Johnston, SL;Chalmers, JD;Singanayagam, A; Neutrophil extracellular traps promote immunopathogenesis of virus-induced COPD exacerbations Nature communications 2024-07-09 [PMID: 38982052] (Human)
• Bosselaar, S;Dhelin, L;Dautel, E;Titecat, M;Duthoy, S;Stelmaszczyk, M;Delory, N;De Sousa Violante, M;Machuron, F;Ait-Abderrahim, H;Desreumaux, P;Foligné, B;Monnet, C; Taxonomic and phenotypic analysis of bifidobacteria isolated from IBD patients as potential probiotic strains BMC microbiology 2024-06-29 [PMID: 38951788] (Human)
• Halasz, H;Malekos, E;Covarrubias, S;Yitiz, S;Montano, C;Sudek, L;Katzman, S;Liu, SJ;Horlbeck, MA;Namvar, L;Weissman, JS;Carpenter, S; CRISPRi screens identify the lncRNA, LOUP, as a multifunctional locus regulating macrophage differentiation and inflammatory signaling Proceedings of the National Academy of Sciences of the United States of America 2024-05-28 [PMID: 38781216] (Human)
• Marinho, A;Seabra, CL;Lima, SAC;Lobo-da-Cunha, A;Reis, S;Nunes, C; Empowering Naringin's Anti-Inflammatory Effects through Nanoencapsulation International journal of molecular sciences 2024-04-09 [PMID: 38673736] (Human)
• Roos, J;Zinngrebe, J;Huber-Lang, M;Lupu, L;Schmidt, MA;Strobel, H;Westhoff, MA;Stifel, U;Gebhard, F;Wabitsch, M;Mollnes, TE;Debatin, KM;Halbgebauer, R;Fischer-Posovszky, P; Trauma-associated extracellular histones mediate inflammation via a MYD88-IRAK1-ERK signaling axis and induce lytic cell death in human adipocytes Cell death & disease 2024-04-23 [PMID: 38653969] (Human)
• De, K;Belardinelli, JM;Pandurangan, AP;Ehianeta, T;Lian, E;Pal?eková, Z;Lam, H;Gonzalez-Juarrero, M;Bryant, JM;Blundell, TL;Parkhill, J;Floto, RA;Lowary, TL;Wheat, WH;Jackson, M; Lipoarabinomannan modification as a source of phenotypic heterogeneity in host-adapted Mycobacterium abscessus isolates Proceedings of the National Academy of Sciences of the United States of America 2024-04-23 [PMID: 38630725] (Human)
• Yu, MSC;Chiang, DM;Reithmair, M;Meidert, A;Brandes, F;Schelling, G;Ludwig, C;Meng, C;Kirchner, B;Zenner, C;Muller, L;Pfaffl, MW; The proteome of bacterial membrane vesicles in Escherichia coli-a time course comparison study in two different media Frontiers in microbiology 2024-03-06 [PMID: 38510998] (Human)
• Li, Z;Barnaby, R;Nymon, A;Roche, C;Koeppen, K;Ashare, A;Hogan, DA;Gerber, SA;Taatjes, DJ;Hampton, TH;Stanton, BA; P. aeruginosa tRNA-fMet halves secreted in outer membrane vesicles suppress lung inflammation in Cystic Fibrosis bioRxiv : the preprint server for biology 2024-02-03 [PMID: 38352468] (Human)
• Vicariotto, F;Malfa, P;Viciani, E;Dell'Atti, F;Squarzanti, DF;Marcante, A;Castagnetti, A;Ponchia, R;Governini, L;De Leo, V; Efficacy of Lactiplantibacillus plantarum PBS067, Bifidobacterium animalis subsp. lactis BL050, and Lacticaseibacillus rhamnosus LRH020 in the Amelioration of Vaginal Microbiota in Post-Menopausal Women: A Prospective Observational Clinical Trial Nutrients 2024-01-30 [PMID: 38337685] (Human)
• Zhang, Y;Bharathi, V;Dokoshi, T;de Anda, J;Ursery, LT;Kulkarni, NN;Nakamura, Y;Chen, J;Luo, EWC;Wang, L;Xu, H;Coady, A;Zurich, R;Lee, MW;Matsui, T;Lee, H;Chan, LC;Schepmoes, AA;Lipton, MS;Zhao, R;Adkins, JN;Clair, GC;Thurlow, LR;Schisler, JC;Wolfgang, MC;Hagan, RS;Yeaman, MR;Weiss, TM;Chen, X;Li, MMH;Nizet, V;Antoniak, S;Mackman, N;Gallo, RL;Wong, GCL; Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes Proceedings of the National Academy of Sciences of the United States of America 2024-02-06 [PMID: 38306481] (Human)
• Yamamoto, S;Ogasawara, N;Mitsuhashi, Y;Takano, K;Yokota, SI; The clarithromycin-binding proteins NIPSNAP1 and 2 regulate cytokine production through mitochondrial quality control Scientific reports 2024-01-29 [PMID: 38287119] (Human)
• Irwin, S;Chupina Estrada, A;Nelson, B;Bullock, A;Limketkai, B;Ho, W;Acton, S;Chesnel, L;Koon, HW; ADS024, a single-strain live biotherapeutic product of Bacillus velezensis alleviates dextran sulfate-mediated colitis in mice, protects human colonic epithelial cells against apoptosis, and maintains epithelial barrier function Frontiers in microbiology 2024-01-10 [PMID: 38268707] (Human)
• Macrì, F;Vigorito, I;Castiglione, S;Faggiano, S;Casaburo, M;Fanotti, N;Piacentini, L;Vigetti, D;Vinci, MC;Raucci, A; High Phosphate-Induced JAK-STAT Signalling Sustains Vascular Smooth Muscle Cell Inflammation and Limits Calcification Biomolecules 2023-12-24 [PMID: 38254629] (Human)
• Upadhyay, S;Rahman, M;Rinaldi, S;Koelmel, J;Lin, EZ;Mahesh, PA;Beckers, J;Johanson, G;Pollitt, KJG;Palmberg, L;Irmler, M;Ganguly, K; Assessment of wood smoke induced pulmonary toxicity in normal- and chronic bronchitis-like bronchial and alveolar lung mucosa models at air-liquid interface Respiratory research 2024-01-20 [PMID: 38245732] (Human)
• Mahamed, Z;Shadab, M;Najar, RA;Millar, MW;Bal, J;Pressley, T;Fazal, F; The Protective Role of Mitochondria-Associated Endoplasmic Reticulum Membrane (MAM) Protein Sigma-1 Receptor in Regulating Endothelial Inflammation and Permeability Associated with Acute Lung Injury Cells 2023-12-19 [PMID: 38201208] (Human)
• Kim, YT;Huh, JW;Choi, YH;Yoon, HK;Nguyen, TT;Chun, E;Jeong, G;Park, S;Ahn, S;Lee, WK;Noh, YW;Lee, KS;Ahn, HS;Lee, C;Lee, SM;Kim, KS;Suh, GJ;Jeon, K;Kim, S;Jin, M; Highly secreted tryptophanyl tRNA synthetase 1 as a potential theranostic target for hypercytokinemic severe sepsis EMBO molecular medicine 2024-01-01 [PMID: 38177528] (Mouse)
• Jayaram, L;King, PT;Hunt, J;Lim, M;Park, C;Hu, E;Dousha, L;Ha, P;Bartlett, JB;Southcott, AM;Muruganandan, S;Vogrin, S;Rees, MA;Dean, OM;Wong, CA; Evaluation of high dose N- Acetylcysteine on airway inflammation and quality of life outcomes in adults with bronchiectasis: A randomised placebo-controlled pilot study Pulmonary pharmacology & therapeutics 2023-12-22 [PMID: 38141851] (Human)
• Hiniduma, K;Bhalerao, KS;De Silva, PIT;Chen, T;Rusling, JF; Design and Fabrication of a 3D-Printed Microfluidic Immunoarray for Ultrasensitive Multiplexed Protein Detection Micromachines 2023-11-30 [PMID: 38138356] (Human)
• Lee, KS;Kim, Y;Lee, JH;Shon, S;Kim, A;Pham, AVQ;Kim, C;Kim, DH;Kim, YK;Cho, EG; Human Probiotic Lactobacillus paracasei-Derived Extracellular Vesicles Improve Tumor Necrosis Factor-?-Induced Inflammatory Phenotypes in Human Skin Cells 2023-12-07 [PMID: 38132109] (Human)
• Kim, HS;Kim, HJ;Hong, YD;Son, ED;Cho, SY; ?-endorphin suppresses ultraviolet B irradiation-induced epidermal barrier damage by regulating inflammation-dependent mTORC1 signaling Scientific reports 2023-12-15 [PMID: 38102220] (Human)
• Ferraro, M;Di Vincenzo, S;Lazzara, V;Pinto, P;Patella, B;Inguanta, R;Bruno, A;Pace, E; Formoterol Exerts Anti-Cancer Effects Modulating Oxidative Stress and Epithelial-Mesenchymal Transition Processes in Cigarette Smoke Extract Exposed Lung Adenocarcinoma Cells International journal of molecular sciences 2023-11-08 [PMID: 38003276] (Human)
• Cholon, DM;Greenwald, MA;Higgs, MG;Quinney, NL;Boyles, SE;Meinig, SL;Minges, JT;Chaubal, A;Tarran, R;Ribeiro, CMP;Wolfgang, MC;Gentzsch, M; A Novel Co-Culture Model Reveals Enhanced CFTR Rescue in Primary Cystic Fibrosis Airway Epithelial Cultures with Persistent Pseudomonas aeruginosa Infection Cells 2023-11-13 [PMID: 37998353] (Human)
• Obolski, U;Swarthout, TD;Kalizang'oma, A;Mwalukomo, TS;Chan, JM;Weight, CM;Brown, C;Cave, R;Cornick, J;Kamng'ona, AW;Msefula, J;Ercoli, G;Brown, JS;Lourenço, J;Maiden, MC;French, N;Gupta, S;Heyderman, RS; The metabolic, virulence and antimicrobial resistance profiles of colonising Streptococcus pneumoniae shift after PCV13 introduction in urban Malawi Nature communications 2023-11-17 [PMID: 37978177] (Human)
• Zobel, CM;Wenzel, W;Krüger, JP;Baumgarten, U;Wagelöhner, T;Neumann, N;Foroutan, B;Müller, R;Müller, A;Rauschning, D;Schü beta ler, M;Scheit, L;Weinreich, F;Oltmanns, K;Keidel, F;Koch, M;Spethmann, S;Schreiner, M; Serum interleukin-6, procalcitonin, and C-reactive protein at hospital admission can identify patients at low risk for severe COVID-19 progression Frontiers in microbiology 2023-10-23 [PMID: 37937220] (Human)
• Nikiforov, NG;Kirichenko, TV;Kubekina, MV;Chegodaev, YS;Zhuravlev, AD;Ilchuk, LA;Nikolaeva, MA;Arefieva, AS;Popov, MA;Verkhova, SS;Bagheri Ekta, M;Orekhov, AN; Macrophages derived from LPS-stimulated monocytes from individuals with subclinical atherosclerosis were characterized by increased pro-inflammatory activity Cytokine 2023-12-01 [PMID: 37918051] (Human)
• Kwon, JW;Savitri, C;An, B;Yang, SW;Park, K; Mesenchymal stem cell-derived secretomes-enriched alginate/ extracellular matrix hydrogel patch accelerates skin wound healing Biomaterials research 2023-10-31 [PMID: 37904231] (Human)
• Dimasuay, KG;Schaunaman, N;Berg, B;Nichols, T;Chu, HW; Parkin Promotes Airway Inflammatory Response to Interferon Gamma Biomedicines 2023-10-20 [PMID: 37893223] (Human)
• Campesi, I;Capobianco, G;Cano, A;Lodde, V;Cruciani, S;Maioli, M;Sotgiu, G;Idda, ML;Puci, MV;Ruoppolo, M;Costanzo, M;Caterino, M;Cambosu, F;Montella, A;Franconi, F; Stratification of Amniotic Fluid Cells and Amniotic Fluid by Sex Opens Up New Perspectives on Fetal Health Biomedicines 2023-10-18 [PMID: 37893203] (Human)
• Dumitru, CA;Schröder, H;Schäfer, FTA;Aust, JF;Kre beta e, N;Siebert, CLR;Stein, KP;Haghikia, A;Wilkens, L;Mawrin, C;Sandalcioglu, IE; Progesterone Receptor Membrane Component 1 (PGRMC1) Modulates Tumour Progression, the Immune Microenvironment and the Response to Therapy in Glioblastoma Cells 2023-10-20 [PMID: 37887342] (Human)
• Gabor, CE;Hazen, TH;Delaine-Elias, BC;Rasko, DA;Barry, EM; Genomic, transcriptomic, and phenotypic differences among archetype Shigella flexneri strains of serotypes 2a, 3a, and 6 mSphere 2023-10-13 [PMID: 37830809] (Human)
• Baquer, F;Jaulhac, B;Barthel, C;Paz, M;Wolfgramm, J;Müller, A;Boulanger, N;Grillon, A; Skin microbiota secretomes modulate cutaneous innate immunity against Borrelia burgdorferi s.s Scientific reports 2023-09-29 [PMID: 37773515] (Human)
• Panahipour, L;Botta, S;Abbasabadi, AO;Afradi, Z;Gruber, R; Enamel Matrix Derivative Suppresses Chemokine Expression in Oral Epithelial Cells International journal of molecular sciences 2023-09-12 [PMID: 37762294] (Human)
• Kaneki, M;Ohira, C;Takahashi, M;Iwashita, N;Takagi, Y;Nagane, M;Uchiyama, J;Fukuyama, T; Therapeutic potential of ozone water treatment in alleviating atopic dermatitis symptoms in mouse models: Exploring its bactericidal and direct anti-inflammatory properties International immunopharmacology 2023-09-14 [PMID: 37716162] (Human)
• Cao, QT;Ishak, M;Shpilman, I;Hirota, JA; TNF-? and Poly(I:C) induction of A20 and activation of NF-?B signaling are independent of ABCF1 in human airway epithelial cells Scientific reports 2023-09-07 [PMID: 37679460] (Human)
• Shen, CJ;Chan, RH;Lin, BW;Li, NC;Huang, YH;Chang, WC;Chen, BK; Oleic acid-induced metastasis of KRAS/p53-mutant colorectal cancer relies on concurrent KRAS activation and IL-8 expression bypassing EGFR activation Theranostics 2023-08-21 [PMID: 37649607] (Human)
• Leignadier, J;Drago, M;Lesouhaitier, O;Barreau, M;Dashi, A;Worsley, O;Attia-Vigneau, J; Lysine-Dendrimer, a New Non-Aggressive Solution to Rebalance the Microbiota of Acne-Prone Skin Pharmaceutics 2023-08-03 [PMID: 37631297] (Human)
• Williams, MR;Bagood, MD;Enroth, TJ;Bunch, ZL;Jiang, N;Liu, E;Almoughrabie, S;Khalil, S;Li, F;Brinton, S;Cech, NB;Horswill, AR;Gallo, RL; Staphylococcus epidermidis activates keratinocyte cytokine expression and promotes skin inflammation through the production of phenol-soluble modulins Cell reports 2023-08-22 [PMID: 37610872] (Human)
• Siegel, NA;Jimenez, MT;Rocha, CS;Rolston, M;Dandekar, S;Solnick, JV;Miller, LA; Helicobacter pylori Infection in Infant Rhesus Macaque Monkeys is Associated with an Altered Lung and Oral Microbiome Research square 2023-08-07 [PMID: 37609264] (Primate - Macaca mulatta (Rhesus Macaque))
• Faria, J;Ahmed, S;Stamatialis, D;Verhaar, MC;Masereeuw, R;Gerritsen, KGF;Mih?il?, SM; Bioengineered Kidney Tubules Efficiently Clear Uremic Toxins in Experimental Dialysis Conditions International journal of molecular sciences 2023-08-04 [PMID: 37569805] (Human)
• Khan, MT;Dwibedi, C;Sundh, D;Pradhan, M;Kraft, JD;Caesar, R;Tremaroli, V;Lorentzon, M;Bäckhed, F; Synergy and oxygen adaptation for development of next-generation probiotics Nature 2023-08-01 [PMID: 37532933] (Human)
• Zhou, L;Fang, L;Tamm, M;Stolz, D;Roth, M; Extracellular Heat Shock Protein 70 Increases the Glucocorticoid Receptor and Dual-Specificity Phosphatase 1 via Toll-like Receptor 4 and Attenuates Inflammation in Airway Epithelial Cells International journal of molecular sciences 2023-07-20 [PMID: 37511459] (Human)
• Matsunaga, T;Sano, H;Takita, K;Morita, M;Yamanaka, S;Ichikawa, T;Numakura, T;Ida, T;Jung, M;Ogata, S;Yoon, S;Fujino, N;Kyogoku, Y;Sasaki, Y;Koarai, A;Tamada, T;Toyama, A;Nakabayashi, T;Kageyama, L;Kyuwa, S;Inaba, K;Watanabe, S;Nagy, P;Sawa, T;Oshiumi, H;Ichinose, M;Yamada, M;Sugiura, H;Wei, FY;Motohashi, H;Akaike, T; Supersulphides provide airway protection in viral and chronic lung diseases Nature communications 2023-07-25 [PMID: 37491435] (Human)
• Kalsi, KK;Jackson, S;Baines, DL; Lipoxin receptor agonist and inhibition of LTA4 hydrolase prevent tight junction disruption caused by P. aeruginosa filtrate in airway epithelial cells PloS one 2023-07-05 [PMID: 37406028] ( Human)
• Fiorillo, A;Gallego, JJ;Casanova-Ferrer, F;Giménez-Garzó, C;Urios, A;Ballester, MP;Durbán, L;Rios, MP;Megías, J;San Miguel, T;Kosenko, E;Escudero-García, D;Benlloch, S;Felipo, V;Montoliu, C; Mild Cognitive Impairment Is Associated with Enhanced Activation of Th17 Lymphocytes in Non-Alcoholic Fatty Liver Disease International journal of molecular sciences 2023-06-20 [PMID: 37373554] (Human)
• Warren, KJ;Beck, EM;Callahan, SJ;Helms, MN;Middleton, E;Maddock, S;Carr, JR;Harris, D;Blagev, DP;Lanspa, MJ;Brown, SM;Paine, R; Alveolar macrophages from EVALI patients and e-cigarette users: a story of shifting phenotype Respiratory research 2023-06-17 [PMID: 37330506] (Human)
• Jeon, KB;Kim, J;Lim, CM;Park, JY;Kim, NY;Lee, J;Oh, DK;Yoon, DY; Unsaturated oxidated fatty acid 12(S)-HETE attenuates TNF-? expression in TNF-?/IFN-?-stimulated human keratinocytes International immunopharmacology 2023-05-17 [PMID: 37207444] (Human)
• Dimasuay, KG;Berg, B;Schaunaman, N;Nichols, T;Chu, HW; Parkin promotes airway inflammatory response to interferon gamma Research square 2023-04-24 [PMID: 37163023] (Human)
• A Di Nardo, YL Chang, S Alimohamma, K Masuda-Kur, Z Wang, K Sriram, PA Insel Mast cell tolerance in the skin microenvironment to commensal bacteria is controlled by fibroblasts Cell Reports, 2023-04-28;42(5):112453. 2023-04-28 [PMID: 37120813] (Human)
• H Han, Y You, S Cha, TR Kim, M Sohn, J Park Multi-Species Probiotic Strain Mixture Enhances Intestinal Barrier Function by Regulating Inflammation and Tight Junctions in Lipopolysaccharides Stimulated Caco-2 Cells Microorganisms, 2023-03-03;11(3):. 2023-03-03 [PMID: 36985228] (Human)
• M Liu, AN Panagopoul, UM Oguz, S Samant, CH Vasa, DK Agrawal, YS Chatzizisi Role of triggering receptor expressed on myeloid cells-1 in the mechanotransduction signaling pathways that link low shear stress with inflammation Scientific Reports, 2023-03-21;13(1):4656. 2023-03-21 [PMID: 36944850] (Human)
• T Pirker, EM Pferschy-W, E Bampali, V Bochkov, R Bauer Glycolipid-enriched fraction of Osmanthus fragrans inhibits LPS-induced expression of inflammatory genes, COX-2, E-selectin, and Interleukin-8 Journal of ethnopharmacology, 2023-03-02;0(0):116328. 2023-03-02 [PMID: 36870464] (Human)
• AJ Heires, D Samuelson, D Villageliu, TM Nordgren, DJ Romberger Agricultural dust derived bacterial extracellular vesicle mediated inflammation is attenuated by DHA Scientific Reports, 2023-02-16;13(1):2767. 2023-02-16 [PMID: 36797300] (Human)
• L Chen, V Shi, S Wang, R Freeman, F Ruiz, K Jayachandr, J Zhang, P Cosper, L Sun, CJ Luke, C Spina, PW Grigsby, JK Schwarz, S Markovina SCCA1/SERPINB3 promotes suppressive immune environment via STAT-dependent chemokine production, blunting the therapy-induced T cell responses bioRxiv : the preprint server for biology, 2023-02-03;0(0):. 2023-02-03 [PMID: 36778224] (Human)
• D Tortolani, C Di Meo, S Standoli, F Ciaramella, S Kadhim, E Hsu, C Rapino, M Maccarrone Rare Phytocannabinoids Exert Anti-Inflammatory Effects on Human Keratinocytes via the Endocannabinoid System and MAPK Signaling Pathway International Journal of Molecular Sciences, 2023-02-01;24(3):. 2023-02-01 [PMID: 36769042] (Human)
• D Hinata, R Fukuda, T Okiyoneda The COPD-Associated Polymorphism Impairs the CFTR Function to Suppress Excessive IL-8 Production upon Environmental Pathogen Exposure International Journal of Molecular Sciences, 2023-01-24;24(3):. 2023-01-24 [PMID: 36768629] (Human)
• S Saberi, M Esmaeili, R Saghiri, F Shekari, M Mohammadi Assessment of the mixed origin of the gastric epithelial extracellular vesicles in acellular transfer of Helicobacter pylori toxins and a systematic review Microbial pathogenesis, 2023-02-08;0(0):106024. 2023-02-08 [PMID: 36758823] (Human)
• B Morgner, J Tittelbach, C Wiegand Induction of psoriasis- and atopic dermatitis-like phenotypes in 3D skin equivalents with a fibroblast-derived matrix Scientific Reports, 2023-01-31;13(1):1807. 2023-01-31 [PMID: 36720910] (Human)
• G Bredeck, M Busch, A Rossi, B Stahlmecke, KW Fomba, H Herrmann, RPF Schins Inhalable Saharan dust induces oxidative stress, NLRP3 inflammasome activation, and inflammatory cytokine release Environment international, 2023-01-11;172(0):107732. 2023-01-11 [PMID: 36680803] (Human)
• M Liu, S Samant, CH Vasa, RM Pedrigi, UM Oguz, S Ryu, T Wei, DR Anderson, DK Agrawal, YS Chatzizisi Co-culture models of endothelial cells, macrophages, and vascular smooth muscle cells for the study of the natural history of atherosclerosis PLoS ONE, 2023-01-20;18(1):e0280385. 2023-01-20 [PMID: 36662769] (Human)
• TTT Nguyen, YH Choi, WK Lee, Y Ji, E Chun, YH Kim, JE Lee, HS Jung, JH Suh, S Kim, M Jin Tryptophan-dependent and -independent secretions of tryptophanyl- tRNA synthetase mediate innate inflammatory responses Cell Reports, 2022-12-30;42(1):111905. 2022-12-30 [PMID: 36640342] (Human)
• DT Spiegelbur, M Mannes, A Schultze, F Scheibenbe, F Müller, A Klitzing, DAC Messerer, K Nilsson Ek, B Nilsson, M Huber-Lang, CK Braun Impact of surface coating and systemic anticoagulants on hemostasis and inflammation in a human whole blood model PLoS ONE, 2023-01-12;18(1):e0280069. 2023-01-12 [PMID: 36634087] (Human)
• K Shabir, S Gharanei, S Orton, V Patel, P Chauhan, E Karteris, HS Randeva, JE Brown, I Kyrou Asprosin Exerts Pro-Inflammatory Effects in THP-1 Macrophages Mediated via the Toll-like Receptor 4 (TLR4) Pathway International Journal of Molecular Sciences, 2022-12-23;24(1):. 2022-12-23 [PMID: 36613673] (Human)
• Q Huang, M Peng, Y Gu, J Wu, Y Zhan, Z Deng, S Chen, R Yang, J Chen, J Xie Metabolism-Related Gene TXNRD1 Regulates Inflammation and Oxidative Stress Induced by Cigarette Smoke through the Nrf2/HO-1 Pathway in the Small Airway Epithelium Oxidative Medicine and Cellular Longevity, 2022-12-19;2022(0):7067623. 2022-12-19 [PMID: 36578523] (Human)
• LAC Teixeira, JM Dos Santos, AN Parentoni, LP Lima, TC Duarte, FP Brant, CDC Neves, FSM Pereira, NCP Avelar, AL Danielewic, AAO Leopoldino, SP Costa, AN Arrieiro, LA Soares, ACN Prates, JNP Nobre, A de Carvalh, VC de Oliveir, MX Oliveira, PH Scheidt Fi, HS Costa, V Amaral Men, R Taiar, AC Rodrigues Adiponectin Is a Contributing Factor of Low Appendicular Lean Mass in Older Community-Dwelling Women: A Cross-Sectional Study Journal of Clinical Medicine, 2022-12-02;11(23):. 2022-12-02 [PMID: 36498747] (Human)
• LU Teufel, CI van der Ma, V Klück, A Simons, A Hoischen, V Vernimmen, LAB Joosten, RJW Arts Effect of exogenous IL-37 on immune cells from a patient carrying a potential IL37 loss-of-function variant: A case study Cytokine, 2022-12-05;162(0):156102. 2022-12-05 [PMID: 36476991] (Human)
• T Luong, E Cukierman Eribulin normalizes pancreatic cancer-associated fibroblasts by simulating selected features of TGFbeta inhibition BMC Cancer, 2022-12-02;22(1):1255. 2022-12-02 [PMID: 36461015] (Human)
• E Fournier, J Ratel, S Denis, M Leveque, P Ruiz, C Mazal, F Amiard, M Edely, V Bezirard, E Gaultier, B Lamas, E Houdeau, E Engel, F Lagarde, L Etienne-Me, M Mercier-Bo, S Blanquet-D Exposure to polyethylene microplastics alters immature gut microbiome in an infant in vitro gut model Journal of Hazardous Materials, 2022-11-11;443(0):130383. 2022-11-11 [PMID: 36444070] (Human)
• KEC Blokland, M Nizamoglu, H Habibie, T Borghuis, M Schuliga, BN Melgert, DA Knight, CA Brandsma, SD Pouwels, JK Burgess Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts Frontiers in Pharmacology, 2022-11-03;13(0):989169. 2022-11-03 [PMID: 36408252] (Human)
• B Saravi, Z Li, V Basoli, S Grad, S Häckel, CE Albers, M Alini, H Schmal, P Obid, G Lang In Vitro Characterization of a Tissue Renin-Angiotensin System in Human Nucleus Pulposus Cells Cells, 2022-10-28;11(21):. 2022-10-28 [PMID: 36359814] (Human)
• M Hornschuh, V Haas, PP Winkel, MY Gökyildiri, CS Mullins, IM Wrobel, C Manteuffel, E Wirthgen Negative Magnetic Sorting Preserves the Functionality of Ex Vivo Cultivated Non-Adherent Human Monocytes Biology, 2022-10-27;11(11):. 2022-10-27 [PMID: 36358284] (Human)
• J Yang, L Jin, HS Kim, F Tian, Z Yi, K Bedi, M Ljungman, M Pasca di M, H Crawford, J Shi KDM6A Loss Recruits Tumor-Associated Neutrophils and Promotes Neutrophil Extracellular Trap Formation in Pancreatic Cancer Cancer Research, 2022-11-15;0(0):OF1-OF14. 2022-11-15 [PMID: 36306422] (Human)
• TY Chu, C Zheng-Géra, KY Huang, YC Chang, YW Chen, KY I, YL Lo, NY Chiang, HY Chen, M Stacey, S Gordon, WY Tseng, CY Sun, YM Wu, YS Pan, CH Huang, CY Lin, TC Chen, K El Omari, M Antonelou, SR Henderson, A Salama, E Seiradake, HH Lin GPR97 triggers inflammatory processes in human neutrophils via a macromolecular complex upstream of PAR2 activation Nature Communications, 2022-10-27;13(1):6385. 2022-10-27 [PMID: 36302784] (Human)
• AA Lozhkov, MA Plotnikova, MA Egorova, IL Baranovska, EA Elpaeva, SA Klotchenko, AV Vasin Simultaneous Detection of RIG-1, MDA5, and IFIT-1 Expression Is a Convenient Tool for Evaluation of the Interferon-Mediated Response Viruses, 2022-09-21;14(10):. 2022-09-21 [PMID: 36298646] (Human)
• L Zuliani-Al, ML Govasli, J Rasaiyaah, C Monit, SO Perry, RP Sumner, S McAlpine-S, C Dickson, KM Rifat Fays, L Hilditch, RJ Miles, F Bibollet-R, BH Hahn, T Boecking, N Pinotsis, LC James, DA Jacques, GJ Towers Evasion of cGAS and TRIM5 defines pandemic HIV Nature Microbiology, 2022-10-26;7(11):1762-1776. 2022-10-26 [PMID: 36289397] (Human)
• E Fournier, M Leveque, P Ruiz, J Ratel, C Durif, S Chalancon, F Amiard, M Edely, V Bezirard, E Gaultier, B Lamas, E Houdeau, F Lagarde, E Engel, L Etienne-Me, S Blanquet-D, M Mercier-Bo Microplastics: What happens in the human digestive tract? First evidences in adults using in vitro gut models Journal of Hazardous Materials, 2022-09-21;442(0):130010. 2022-09-21 [PMID: 36182891] (Human)
• M Patankar, M Li, A Khalatbari, JD Castle, L Hu, C Zhang, A Shaker Inflammatory and Proliferative Pathway Activation in Human Esophageal Myofibroblasts Treated with Acidic Bile Salts International Journal of Molecular Sciences, 2022-09-08;23(18):. 2022-09-08 [PMID: 36142285] (Human)
• P Marona, J Górka, O Kwapisz, J Jura, J Rys, RM Hoffman, K Miekus Resistance to tyrosine kinase inhibitors promotes renal cancer progression through MCPIP1 tumor-suppressor downregulation and c-Met activation Cell Death & Disease, 2022-09-22;13(9):814. 2022-09-22 [PMID: 36138026] (Human, Mouse)
• ASI Salgado, MH Takemoto, CFTC de Souza, DC Salm, D da Rosa, GC Cardoso, DD Ludtke, SFC Soares, JK Ferreira, AR Dutra, YC Szeremeta, G Mazzardo, J Mayra, DDL Sheffer, W Caumo, EB Bittencour, R Schleip, A Latini, F Bobinski, DF Martins Gentle Touch Therapy, Pain Relief and Neuroplasticity at Baseline in Fibromyalgia Syndrome: A Randomized, Multicenter Trial with Six-Month Follow-Up Journal of Clinical Medicine, 2022-08-20;11(16):. 2022-08-20 [PMID: 36013137] (Human)
• L Sansone, A de Iure, M Cristina, M Belli, L Vitiello, F Marcolongo, A Rosellini, L Macera, PG Spezia, C Tomino, S Bonassi, MA Russo, F Maggi, P Russo Nicotine in Combination with SARS-CoV-2 Affects Cells Viability, Inflammatory Response and Ultrastructural Integrity International Journal of Molecular Sciences, 2022-08-22;23(16):. 2022-08-22 [PMID: 36012747] (Human)
• C Amormino, V Tedeschi, G Paldino, S Arcieri, MT Fiorillo, A Paiardini, L Tuosto, M Kunkl SARS-CoV-2 Spike Does Not Possess Intrinsic Superantigen-like Inflammatory Activity Cells, 2022-08-15;11(16):. 2022-08-15 [PMID: 36010602] (Human)
• M Busch, G Bredeck, F Waag, K Rahimi, H Ramachandr, T Bessel, S Barcikowsk, A Herrmann, A Rossi, RPF Schins Assessing the NLRP3 Inflammasome Activating Potential of a Large Panel of Micro- and Nanoplastics in THP-1 Cells Biomolecules, 2022-08-09;12(8):. 2022-08-09 [PMID: 36008988] (Human)
• KG Dimasuay, N Schaunaman, B Berg, D Cervantes, E Kruger, FL Heppner, DA Ferrington, HW Chu Airway epithelial immunoproteasome subunit LMP7 protects against rhinovirus infection Scientific Reports, 2022-08-25;12(1):14507. 2022-08-25 [PMID: 36008456] (Human)
• DC Humphries, R Mills, C Boz, BJ McHugh, N Hirani, AG Rossi, A Pedersen, HT Schambye, RJ Slack, H Leffler, UJ Nilsson, W Wang, T Sethi, AC Mackinnon Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation Frontiers in Pharmacology, 2022-08-08;13(0):949264. 2022-08-08 [PMID: 36003515] (Mouse)
• JK Pfromm, M Bonillo, D Dauletbeko, K Bucher, MD Fischer Plasmid-mediated gene transfer of Cas9 induces vector-related but not SpCas9-related immune responses in human retinal pigment epithelial cells Scientific Reports, 2022-08-01;12(1):13202. 2022-08-01 [PMID: 35915300] (Human)
• Y Lyu, Y Chen Digested Human Colostrum Reduces Interleukin-8 Production in Induced Human Intestinal Epithelial Cells Nutrients, 2022-07-06;14(14):. 2022-07-06 [PMID: 35889744] (Human)
• K Ueno-Shuto, S Kamei, M Hayashi, A Fukuyama, Y Uchida, N Tokutomi, MA Suico, H Kai, T Shuto A Splice Switch in SIGIRR Causes a Defect of IL-37-Dependent Anti-Inflammatory Activity in Cystic Fibrosis Airway Epithelial Cells International Journal of Molecular Sciences, 2022-07-13;23(14):. 2022-07-13 [PMID: 35887095] (Human)
• M Anselmi, F Fontana, M Marzagalli, N Gagliano, M Sommariva, P Limonta Melanoma Stem Cells Educate Neutrophils to Support Cancer Progression Cancers, 2022-07-13;14(14):. 2022-07-13 [PMID: 35884452] (Human)
• S Rutecki, P Szulc, M Paku?a, P Uruski, A Radziemski, E Naumowicz, R Moszy?ski, A Tykarski, J Miku?a-Pie, K Ksi??ek Pro-cancerogenic effects of spontaneous and drug-induced senescence of ovarian cancer cells in vitro and in vivo: a comparative analysis Journal of ovarian research, 2022-07-26;15(1):87. 2022-07-26 [PMID: 35883110] (Human)
• EM Smith, CL Grassel, A Papadimas, J Foulke-Abe, EM Barry The role of CFA/I in adherence and toxin delivery by ETEC expressing multiple colonization factors in the human enteroid model PloS Neglected Tropical Diseases, 2022-07-26;16(7):e0010638. 2022-07-26 [PMID: 35881640] (Human)
• LAJ Feather, V Nadella, E Kastner, Y Perrie, AC Hilton, A Devitt Development of a rapid in vitro pre-screen for distinguishing effective liposome-adjuvant delivery systems Scientific Reports, 2022-07-20;12(1):12448. 2022-07-20 [PMID: 35859154] (Human)
• H Stölting, L Baillon, R Frise, K Bonner, RJ Hewitt, PL Molyneaux, ML Gore, Breathing, WS Barclay, S Saglani, CM Lloyd Distinct airway epithelial immune responses after infection with SARS-CoV-2 compared to H1N1 Mucosal Immunology, 2022-07-15;0(0):. 2022-07-15 [PMID: 35840680] (Human)
• A Moniot, J Braux, R Siboni, C Guillaume, S Audonnet, I Allart-Sim, J Sapi, R Tirouvanzi, S Gérard, SC Gangloff, F Velard Inhibition of Recruitment and Activation of Neutrophils by Pyridazinone-Scaffold-Based Compounds International Journal of Molecular Sciences, 2022-06-29;23(13):. 2022-06-29 [PMID: 35806233] (Human)
• S Upadhyay, A Chakrabort, TA Thimraj, M Baldi, A Steneholm, K Ganguly, P Gerde, L Ernstgård, L Palmberg Establishment of Repeated In Vitro Exposure System for Evaluating Pulmonary Toxicity of Representative Criteria Air Pollutants Using Advanced Bronchial Mucosa Models Oncogene, 2022-05-24;10(6):. 2022-05-24 [PMID: 35736886] (Human)
• JT de Kay, J Carver, B Shevenell, AM Kosta, S Tsibulniko, E Certo, DB Sawyer, S Ryzhov, MP Robich Decreased expression of ErbB2 on left ventricular epicardial cells in patients with diabetes mellitus Cellular Signalling, 2022-05-21;96(0):110360. 2022-05-21 [PMID: 35609807] (Human)
• Q Liu, L Hua, C Bao, L Kong, J Hu, C Liu, Z Li, S Xu, X Liu Inhibition of Spleen Tyrosine Kinase Restores Glucocorticoid Sensitivity to Improve Steroid-Resistant Asthma Frontiers in Pharmacology, 2022-05-05;13(0):885053. 2022-05-05 [PMID: 35600871] (Human)
• L Homann, M Rentschler, E Brenner, K Böhm, M Röcken, T Wieder IFN-gamma and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma Cells, 2022-04-30;11(9):. 2022-04-30 [PMID: 35563820] (Human)
• E Filidou, L Kandilogia, G Tarapatzi, M Spathakis, P Steiropoul, D Mikroulis, K Arvanitidi, V Paspaliari, G Kolios Anti-Inflammatory and Anti-Fibrotic Effect of Immortalized Mesenchymal-Stem-Cell-Derived Conditioned Medium on Human Lung Myofibroblasts and Epithelial Cells International Journal of Molecular Sciences, 2022-04-20;23(9):. 2022-04-20 [PMID: 35562961] (Human)
• Y Zhan, J Chen, J Wu, Y Gu, Q Huang, Z Deng, S Chen, X Wu, Y Lv, Z Zeng, J Xie Human epididymis protein 4 aggravates airway inflammation and remodeling in chronic obstructive pulmonary disease Respiratory Research, 2022-05-12;23(1):120. 2022-05-12 [PMID: 35550579] (Human)
• S Novello, S Tricot-Dol, A Novella, P Pellen-Mus, S Jeanne Influence of Periodontal Ligament Stem Cell-Derived Conditioned Medium on Osteoblasts Pharmaceutics, 2022-03-28;14(4):. 2022-03-28 [PMID: 35456563] (Human)
• K Nakamura, H Nakayama, S Sasaki, K Takahashi, K Iwabuchi Mycobacterium avium-intracellulare complex promote release of pro-inflammatory enzymes matrix metalloproteinases by inducing neutrophil extracellular trap formation Scientific Reports, 2022-04-11;12(1):5181. 2022-04-11 [PMID: 35410994] (Human)
• M Dolci, L Signorini, S D'Alessand, F Perego, S Parapini, M Sommariva, D Taramelli, P Ferrante, N Basilico, S Delbue In Vitro SARS-CoV-2 Infection of Microvascular Endothelial Cells: Effect on Pro-Inflammatory Cytokine and Chemokine Release International Journal of Molecular Sciences, 2022-04-06;23(7):. 2022-04-06 [PMID: 35409421] (Human)
• H Janbazacya, J van Bergen, S Varasteh, J Garssen, G Folkerts, S Braber Repeated exposure of bronchial epithelial cells to particular matter increases allergen-induced cytokine release and permeability Cytokine, 2022-04-08;154(0):155878. 2022-04-08 [PMID: 35405483] (Human)
• P Globig, R Willumeit-, F Martini, E Mazzoni, BJC Luthringer Slow degrading Mg-based materials induce tumor cell dormancy on an osteosarcoma-fibroblast coculture model Bioactive materials, 2021-12-30;16(0):320-333. 2021-12-30 [PMID: 35386318] (Human)
• T Walle, JA Kraske, B Liao, B Lenoir, C Timke, E von Bohlen, F Tran, P Griebel, D Albrecht, A Ahmed, M Suarez-Car, A Jiménez-Sá, T Beikert, A Tietz-Dahl, AN Menevse, G Schmidt, M Brom, JHW Pahl, W Antonopoul, M Miller, RL Perez, F Bestvater, NA Giese, P Beckhove, P Rosenstiel, D Jäger, O Strobel, D Pe'er, N Halama, J Debus, A Cerwenka, PE Huber Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8 Science Advances, 2022-03-23;8(12):eabh4050. 2022-03-23 [PMID: 35319989] (Human)
• A Divoux, E Erdos, K Whytock, TF Osborne, SR Smith Transcriptional and DNA Methylation Signatures of Subcutaneous Adipose Tissue and Adipose-Derived Stem Cells in PCOS Women Cells, 2022-03-01;11(5):. 2022-03-01 [PMID: 35269469] (Human)
• AR Cátala-Val, J Almeda, JN Bernard, AM Cole, AL Cole, SD Moore, CD Andl E-Cigarette Aerosols Promote Oral S. aureus Colonization by Delaying an Immune Response and Bacterial Clearing Cells, 2022-02-23;11(5):. 2022-02-23 [PMID: 35269394] (Human)
• E Lieschke, Z Wang, C Chang, CE Weeden, GL Kelly, A Strasser Flow cytometric single cell-based assay to simultaneously detect cell death, cell cycling, DNA content and cell senescence Cell Death and Differentiation, 2022-03-09;0(0):. 2022-03-09 [PMID: 35264779] (Human)
• G Szylar, R Wysoczansk, H Marshall, DJB Marks, R José, ME Ehrenstein, JS Brown A novel Streptococcus pneumoniae human challenge model demonstrates Treg lymphocyte recruitment to the infection site Scientific Reports, 2022-03-07;12(1):3990. 2022-03-07 [PMID: 35256717] (Human)
• OF McElvaney, T Asakura, SL Meinig, JL Torres-Cas, RS Hagan, C Gabillard, MP Murphy, LB Thorne, A Borczuk, EP Reeves, RE Zumwalt, Y Mikami, TP Carroll, K Okuda, G Hogan, OJ McElvaney, J Clarke, NL McEvoy, PW Mallon, C McCarthy, G Curley, MC Wolfgang, RC Boucher, NG McElvaney Protease-anti-protease compartmentalization in SARS-CoV-2 ARDS: Therapeutic implications EBioMedicine, 2022-02-22;77(0):103894. 2022-02-22 [PMID: 35217407] (Human)
• C Sun, M Janjic Ran, M Folwaczny, T Stocker, S Otto, A Wichelhaus, U Baumert Effect of Different Parameters of In Vitro Static Tensile Strain on Human Periodontal Ligament Cells Simulating the Tension Side of Orthodontic Tooth Movement International Journal of Molecular Sciences, 2022-01-28;23(3):. 2022-01-28 [PMID: 35163446] (Human)
• S Saxena, C Molczyk, A Purohit, E Ehrhorn, P Goel, DR Prajapati, P Atri, S Kaur, PM Grandgenet, MA Hollingswo, SK Batra, RK Singh Differential expression profile of CXC-receptor-2 ligands as potential biomarkers in pancreatic ductal adenocarcinoma American journal of cancer research, 2022-01-15;12(1):68-90. 2022-01-15 [PMID: 35141005] (Human)
• J Queen, JC Domingue, JR White, C Stevens, B Udayasurya, TTD Nguyen, S Wu, H Ding, H Fan, M McMann, A Corona, TC Larman, SS Verbridge, F Housseau, DJ Slade, JL Drewes, CL Sears Comparative Analysis of Colon Cancer-Derived Fusobacterium nucleatum Subspecies: Inflammation and Colon Tumorigenesis in Murine Models MBio, 2022-02-08;0(0):e0299121. 2022-02-08 [PMID: 35130731] (Human)
• S Hong, KH Park, YE Lee, JE Lee, YM Kim, E Joo, I Cho Antibody microarray analysis of amniotic fluid proteomes in women with cervical insufficiency and short cervix, and their association with pregnancy latency length PLoS ONE, 2022-02-07;17(2):e0263586. 2022-02-07 [PMID: 35130326] (Human)
• V Schimek, K Strasser, A Beer, S Göber, N Walterskir, C Brostjan, C Müller, T Bachleitne, M Bergmann, H Dolznig, R Oehler Tumour cell apoptosis modulates the colorectal cancer immune microenvironment via interleukin-8-dependent neutrophil recruitment Cell Death & Disease, 2022-02-04;13(2):113. 2022-02-04 [PMID: 35121727] (Human)
• S Offer, E Hartner, S Di Bucchia, C Bisig, S Bauer, J Pantzke, EJ Zimmermann, X Cao, S Binder, E Kuhn, A Huber, S Jeong, U Käfer, P Martens, A Mesceriako, J Bendl, R Brejcha, A Buchholz, D Gat, T Hohaus, N Rastak, G Jakobi, M Kalberer, T Kanashova, Y Hu, C Ogris, A Marsico, F Theis, M Pardo, T Gröger, S Oeder, J Orasche, A Paul, T Ziehm, ZH Zhang, T Adam, O Sippula, M Sklorz, J Schnelle-K, H Czech, A Kiendler-S, Y Rudich, R Zimmermann Effect of Atmospheric Aging on Soot Particle Toxicity in Lung Cell Models at the Air-Liquid Interface: Differential Toxicological Impacts of Biogenic and Anthropogenic Secondary Organic Aerosols (SOAs) Environmental health perspectives, 2022-02-03;130(2):27003. 2022-02-03 [PMID: 35112925] (Human)
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• Y Gu, J Chen, Q Huang, Y Zhan, T Wang, J Wu, J Zhao, Z Zeng, Y Lv, C Xiao, J Xie MTMR14 Alleviates Chronic Obstructive Pulmonary Disease as a Regulator in Inflammation and Emphysema Oxidative Medicine and Cellular Longevity, 2022-01-07;2022(0):9300269. 2022-01-07 [PMID: 35035670] (Human)
• ME Nordberg, M Täubel, S Heikkinen, K Jalkanen, A Köliö, M Stranger, H Leppänen, A Hyvärinen, K Huttunen Toxicological transcriptome of human airway constructs after exposure to indoor air particulate matter: In search of relevant pathways of moisture damage-associated health effects Environment international, 2021-11-26;158(0):106997. 2021-11-26 [PMID: 34991257] (Human)
• M Rahman, M Irmler, S Keshavan, M Introna, J Beckers, L Palmberg, G Johanson, K Ganguly, S Upadhyay Differential Effect of SARS-CoV-2 Spike Glycoprotein 1 on Human Bronchial and Alveolar Lung Mucosa Models: Implications for Pathogenicity Viruses, 2021-12-17;13(12):. 2021-12-17 [PMID: 34960806] (Human)
• A Tosi, L Nardinocch, ML Carbone, L Capriotti, E Pagani, S Mastroeni, C Fortes, F Scopelliti, C Cattani, F Passarelli, A Rosato, S D'Atri, CM Failla, A Cavani Reduced Interleukin-17-Expressing Cells in Cutaneous Melanoma Biomedicines, 2021-12-16;9(12):. 2021-12-16 [PMID: 34944746] (Human)
• AA Giese, A Babendreye, P Krappen, A Gross, P Strnad, S Düsterhöft, A Ludwig Inflammatory activation of surface molecule shedding by upregulation of the pseudoprotease iRhom2 in colon epithelial cells Scientific Reports, 2021-12-20;11(1):24230. 2021-12-20 [PMID: 34930929] (Human)
• S Saberi, M Esmaeili, M Tashakorip, M Eshagh Hos, H Baharvand, M Mohammadi Infection with a hypervirulent strain of Helicobacter pylori primes gastric cells toward intestinal transdifferentiation Microbial pathogenesis, 2021-12-08;162(0):105353. 2021-12-08 [PMID: 34896202] (Human)
• R Roca-Pinil, R Holani, A López-Cano, C Saubi, R Baltà-Foix, ER Cobo, E Garcia-Fru, A Arís Sequence edition of single domains modulates the final immune and antimicrobial potential of a new generation of multidomain recombinant proteins Scientific Reports, 2021-12-10;11(1):23798. 2021-12-10 [PMID: 34893661] (Human)
• K Dull, F Fazekas, D Deák, D Kovács, S Póliska, A Szegedi, CC Zouboulis, D Tör?csik miR-146a modulates TLR1/2 and 4 induced inflammation and links it with proliferation and lipid production via the indirect regulation of GNG7 in human SZ95 sebocytes Scientific Reports, 2021-11-02;11(1):21510. 2021-11-02 [PMID: 34728702] (Human)
• X Zhu, Y Zhan, Y Gu, Q Huang, T Wang, Z Deng, J Xie Cigarette Smoke Promotes Interleukin-8 Production in Alveolar Macrophages Through the Reactive Oxygen Species/Stromal Interaction Molecule 1/Ca2+ Axis Frontiers in Physiology, 2021-10-08;12(0):733650. 2021-10-08 [PMID: 34690806] (Human)
• SR Bruno, A Kumar, ZF Mark, R Chandrasek, E Nakada, N Chamberlai, B Mihavics, J Walzer, J Cahoon, AE Dixon, B Cunniff, V Anathy DRP1-Mediated Mitochondrial Fission Regulates Lung Epithelial Response to Allergen International Journal of Molecular Sciences, 2021-10-15;22(20):. 2021-10-15 [PMID: 34681784] (Human)
• L Liu, E Bankell, C Rippe, B Morén, KG Stenkula, BO Nilsson, K Swärd Cell Type Dependent Suppression of Inflammatory Mediators by Myocardin Related Transcription Factors Frontiers in Physiology, 2021-10-04;12(0):732564. 2021-10-04 [PMID: 34671275] (Human)
• S McKenna, SP Giblin, RA Bunn, Y Xu, SJ Matthews, JE Pease A highly efficient method for the production and purification of recombinant human CXCL8 PLoS ONE, 2021-10-15;16(10):e0258270. 2021-10-15 [PMID: 34653205] (Human)
• Claire M. Mulvey, Lisa M. Breckels, Oliver M. Crook, David J. Sanders, Andre L. R. Ribeiro, Aikaterini Geladaki et al. Spatiotemporal proteomic profiling of the pro-inflammatory response to lipopolysaccharide in the THP-1 human leukaemia cell line Nature Communications 2021-10-01 [PMID: 34599159] (Human)
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• N Niu, J Yao, RC Bast, AK Sood, J Liu IL-6 promotes drug resistance through formation of polyploid giant cancer cells and stromal fibroblast reprogramming Oncogenesis, 2021-09-29;10(9):65. 2021-09-29 [PMID: 34588424] (Human)
• MS Shaban, C Müller, C Mayr-Buro, H Weiser, J Meier-Soel, BV Albert, A Weber, U Linne, T Hain, I Babayev, N Karl, N Hofmann, S Becker, S Herold, ML Schmitz, J Ziebuhr, M Kracht Multi-level inhibition of coronavirus replication by chemical ER stress Nature Communications, 2021-09-20;12(1):5536. 2021-09-20 [PMID: 34545074] (Human)
• MAR Brandao-Ra, R Moraes-Fer, MC Oliveira-J, A Santos-Dia, ALL Bachi, G Gabriela-P, S de Oliveir, AC Araújo-Ros, LVF Oliveira, CR Frison, WL do Prado, RP Raju, PB Balagopal, RP Vieira Pulmonary function changes in older adults with and without metabolic syndrome Scientific Reports, 2021-08-30;11(1):17337. 2021-08-30 [PMID: 34462482] (Human)
• N Rufo, D Korovesis, S Van Eygen, R Derua, AD Garg, F Finotello, M Vara-Perez, J Rožanc, M Dewaele, PA de Witte, LG Alexopoulo, S Janssens, L Sinkkonen, T Sauter, SHL Verhelst, P Agostinis Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1alpha kinase inhibitor KIRA6 through HSP60 targeting Cell Death and Differentiation, 2021-08-27;0(0):. 2021-08-27 [PMID: 34453119] (Human)
• E Wirthgen, M Hornschuh, IM Wrobel, C Manteuffel, J Däbritz Mimicking of Blood Flow Results in a Distinct Functional Phenotype in Human Non-Adherent Classical Monocytes Biology, 2021-08-04;10(8):. 2021-08-04 [PMID: 34439980] (Human)
• M Lesouhaiti, M Gregoire, A Gacouin, V Coirier, A Frerou, C Piau, V Cattoir, E Dumontet, M Revest, P Tattevin, A Roisne, JP Verhoye, E Flecher, Y Le Tulzo, K Tarte, JM Tadié Neutrophil function and bactericidal activity against Staphylococcus aureus after cardiac surgery with cardiopulmonary bypass Journal of leukocyte biology, 2021-08-23;0(0):. 2021-08-23 [PMID: 34425029] (Human)
• G Dunsmore, EP Rosero, S Shahbaz, DM Santer, J Jovel, P Lacy, S Houston, S Elahi Neutrophils promote T-cell activation through the regulated release of CD44-bound Galectin-9 from the cell surface during HIV infection PloS Biology, 2021-08-19;19(8):e3001387. 2021-08-19 [PMID: 34411088] (Human)
• AF Santos, NSR Santos Mot, EM Schiefer, RS da Cunha, AM Junkert, AEM Stinghen, R Pontarolo, AR Crisma, AM Weffort-Sa, RC Pedrosa, WM de Souza, KB Felipe The toxicity of Aspidosperma subincanum to MCF7 cells is related to modulation of oxidative status and proinflammatory pathways Journal of ethnopharmacology, 2021-08-09;0(0):114512. 2021-08-09 [PMID: 34384848] (Human)
• Z Cui, H Dabas, BC Leonard, JV Shiah, JR Grandis, DE Johnson Caspase-8 mutations associated with head and neck cancer differentially retain functional properties related to TRAIL-induced apoptosis and cytokine induction Cell Death & Disease, 2021-08-06;12(8):775. 2021-08-06 [PMID: 34362880] (Human)
• L Kandilogia, E Filidou, I Drygiannak, G Tarapatzi, S Didaskalou, M Koffa, K Arvanitidi, G Bamias, V Valatas, V Paspaliari, G Kolios Development of a Human Intestinal Organoid Model for In Vitro Studies on Gut Inflammation and Fibrosis Stem Cells International, 2021-07-27;2021(0):9929461. 2021-07-27 [PMID: 34354753] (Human)
• J Cui, C Duizer, LI Bouwman, KS van Rooije, CGP Voogdt, JPM van Putten, MR de Zoete The ALPK1 pathway drives the inflammatory response to Campylobacter jejuni in human intestinal epithelial cells PloS Pathogens, 2021-08-02;17(8):e1009787. 2021-08-02 [PMID: 34339468] (Human)
• Y Hosokawa, I Hosokawa, K Ozaki Nobiletin Decreases Inflammatory Mediator Expression in Tumor Necrosis Factor-Stimulated Human Periodontal Ligament Cells Mediators of Inflammation, 2021-07-10;2021(0):5535844. 2021-07-10 [PMID: 34335088] (Human)
• B Falcones, H Sanz-Frail, E Marhuenda, I Mendizábal, I Cabrera-Ag, N Malandain, JJ Uriarte, I Almendros, D Navajas, DJ Weiss, R Farré, J Otero Bioprintable Lung Extracellular Matrix Hydrogel Scaffolds for 3D Culture of Mesenchymal Stromal Cells Polymers, 2021-07-18;13(14):. 2021-07-18 [PMID: 34301107] (Human)
• X He, BA Howard, Y Liu, AK Neumann, L Li, N Menon, T Roach, SD Kale, DC Samuels, H Li, T Kite, H Kita, TY Hu, M Luo, CN Jones, UJ Okaa, DL Squillace, BS Klein, CB Lawrence LYSMD3: A mammalian pattern recognition receptor for chitin Cell Reports, 2021-07-20;36(3):109392. 2021-07-20 [PMID: 34289364] (Human)
• JS Bourgeois, L Wang, AF Rabino, J Everitt, MI Alvarez, S Awadia, ES Wittchen, R Garcia-Mat, DC Ko ARHGEF26 enhances Salmonella invasion and inflammation in cells and mice PloS Pathogens, 2021-07-09;17(7):e1009713. 2021-07-09 [PMID: 34242364] (Human)
• LE Cabrera, PT Pekkarinen, M Alander, KHA Nowlan, NA Nguyen, S Jokiranta, S Kuivanen, A Patjas, S Mero, SH Pakkanen, S Heinonen, A Kantele, O Vapalahti, E Kekäläinen, T Strandin Characterization of low-density granulocytes in COVID-19 PloS Pathogens, 2021-07-06;17(7):e1009721. 2021-07-06 [PMID: 34228753] (Human)
• M Busch, AAM Kämpfer, RPF Schins An inverted in vitro triple culture model of the healthy and inflamed intestine: Adverse effects of polyethylene particles Chemosphere, 2021-06-28;284(0):131345. 2021-06-28 [PMID: 34216924] (Mouse)
• KEC Blokland, H Habibie, T Borghuis, GJ Teitsma, M Schuliga, BN Melgert, DA Knight, CA Brandsma, SD Pouwels, JK Burgess Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM Cells, 2021-06-29;10(7):. 2021-06-29 [PMID: 34209854] (Human)
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• YC Hu, IJ Tsai, HY Hsu, BL Chiang, YH Yang Identification of monoclonal antibodies against human renal glomerular endothelial cells in lupus nephritis that induce endothelial interferon-alpha production Arthritis Research & Therapy, 2021-06-16;23(1):171. 2021-06-16 [PMID: 34134755] (Human)
• SL Mathiasen, L Gall-Mas, IS Pateras, SDP Theodorou, MRJ Namini, MB Hansen, OCB Martin, CK Vadivel, K Ntostoglou, D Butter, M Givskov, C Geisler, AN Akbar, VG Gorgoulis, T Frisan, N Ødum, T Krejsgaard Bacterial genotoxins induce T�cell senescence Cell Reports, 2021-06-08;35(10):109220. 2021-06-08 [PMID: 34107253] (Human)
• M Sueiro-Oli, J Scott, S Gago, D Petrovic, E Kouroussis, J Zivanovic, Y Yu, M Strobel, C Cunha, D Thomson, R Fortune-Gr, S Thusek, P Bowyer, A Beilhack, A Carvalho, E Bignell, MR Filipovic, J Amich Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response PloS Biology, 2021-06-01;19(6):e3001247. 2021-06-01 [PMID: 34061822] (Human)
• HK Skovdahl, S Gopalakris, TD Svendsen, AVB Granlund, I Bakke, ZG Ginbot, S Thorsvik, A Flatberg, B Sporsheim, J Ostrop, TE Mollnes, AK Sandvik, T Bruland Patient Derived Colonoids as Drug Testing Platforms-Critical Importance of Oxygen Concentration Frontiers in Pharmacology, 2021-05-13;12(0):679741. 2021-05-13 [PMID: 34054553] (Human)
• L Feng, L Liang, S Zhang, J Yang, Y Yue, X Zhang HMGB1 downregulation in retinal pigment epithelial cells protects against diabetic retinopathy through the autophagy-lysosome pathway Autophagy, 2021-05-24;0(0):1-20. 2021-05-24 [PMID: 34024230] (Rat)
• N Kwak, KH Lee, J Woo, J Kim, CH Lee, CG Yoo Synergistic cycles of protease activity and inflammation via PPAR&gamma degradation in chronic obstructive pulmonary disease Experimental & Molecular Medicine, 2021-05-21;0(0):. 2021-05-21 [PMID: 34021254] (Human)
• S Jamieson, A Mawdesley, D Deehan, J Kirby, J Holland, A Tyson-Capp Inflammatory responses to metal oxide ceramic nanopowders Scientific Reports, 2021-05-18;11(1):10531. 2021-05-18 [PMID: 34006936] (Human)
• W Johnston, BT Rosier, A Artacho, M Paterson, K Piela, C Delaney, JL Brown, G Ramage, A Mira, S Culshaw Mechanical biofilm disruption causes microbial and immunological shifts in periodontitis patients Scientific Reports, 2021-05-07;11(1):9796. 2021-05-07 [PMID: 33963212] (Human)
• T Koudstaal, D van Uden, JAC van Hulst, P Heukels, IM Bergen, LW Geenen, VJM Baggen, AE van den Bo, LM van den To, PP Chandoesin, M Kool, E Boersma, RW Hendriks, KA Boomars Plasma markers in pulmonary hypertension subgroups correlate with patient survival Respiratory Research, 2021-05-04;22(1):137. 2021-05-04 [PMID: 33947407] (Human)
• PH Lee, TY Yang, KC Chen, YH Huang, JS Tseng, KH Hsu, YC Wu, KJ Liu, GC Chang Higher CD4/CD8 ratio of pleural effusion predicts better survival for lung cancer patients receiving immune checkpoint inhibitors Scientific Reports, 2021-04-30;11(1):9381. 2021-04-30 [PMID: 33931705] (Human)
• M Paximadis, ACP Picton, D Sengupta, M Ramsay, A Puren, CT Tiemessen Interleukin-8 genetic diversity, haplotype structure and production differ in two ethnically distinct South African populations Cytokine, 2021-04-01;0(0):155489. 2021-04-01 [PMID: 33814271] (Human)
• SH Kim, SH Hong, JH Lee, DH Lee, K Jung, JY Yang, HS Shin, J Lee, J Jeong, JH Oh Skin Sensitization Evaluation of Carbon-Based Graphene Nanoplatelets Toxics, 2021-03-17;9(3):. 2021-03-17 [PMID: 33803047] (Human)
• M Heydarian, M Schweinlin, T Schwarz, R Rawal, H Walles, M Metzger, T Rudel, V Kozjak-Pav Triple co-culture and perfusion bioreactor for studying the interaction between Neisseria gonorrhoeae and neutrophils: A novel 3D tissue model for bacterial infection and immunity Journal of tissue engineering, 2021-01-28;12(0):2041731420988. 2021-01-28 [PMID: 33796248] (Human)
• X Zhou, LJ Backman, P Danielson Activation of NF-&kapppaB signaling via cytosolic mitochondrial RNA sensing in kerotocytes with mitochondrial DNA common deletion Scientific Reports, 2021-04-01;11(1):7360. 2021-04-01 [PMID: 33795727] (Human)
• L Wang, D Aschenbren, Z Zeng, X Cao, D Mayr, M Mehta, M Capitani, N Warner, J Pan, L Wang, Q Li, T Zuo, S Cohen-Keda, J Lu, RC Ardy, DJ Mulder, D Dissanayak, K Peng, Z Huang, X Li, Y Wang, X Wang, S Li, S Bullers, AN Gammage, K Warnatz, AI Schiefer, G Krivan, V Goda, WHA Kahr, M Lemaire, Genomics E, CY Lu, I Siddiqui, MG Surette, D Kotlarz, KR Engelhardt, HR Griffin, R Rottapel, H Decaluwe, RM Laxer, M Proietti, S Hambleton, S Elcombe, CH Guo, B Grimbacher, I Dotan, SC Ng, SA Freeman, SB Snapper, C Klein, K Boztug, Y Huang, D Li, HH Uhlig, AM Muise Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice Nature Genetics, 2021-03-29;53(4):500-510. 2021-03-29 [PMID: 33782605] (Human)
• PP Nunes, TDM Martins, AC Leite, EBM Silva, TA da Paixão, RL Santos, ÁM Borges Production of IL-1&beta, IL-6 and CXCL8 by endometrium of crossbred heifers stimulated with various pathogen-associated molecular patterns Animal reproduction science, 2021-03-17;228(0):106736. 2021-03-17 [PMID: 33752096] (Bovine)
• M Tong, SE Hanna, VM Abrahams Polymicrobial stimulation of human fetal membranes induce neutrophil activation and neutrophil extracellular trap release Journal of reproductive immunology, 2021-03-09;145(0):103306. 2021-03-09 [PMID: 33725528] (Human)
• GK Vasileiadi, AC Lundell, Y Zhang, K Andersson, I Gjertsson, A Rudin, C Maglio Adipocytokines in Untreated Newly Diagnosed Rheumatoid Arthritis: Association with Circulating Chemokines and Markers of Inflammation Biomolecules, 2021-02-21;11(2):. 2021-02-21 [PMID: 33669910] (Human)
• MS Phuong, RE Hernandez, DJ Wolter, LR Hoffman, S Sad Impairment in inflammasome signaling by the chronic Pseudomonas aeruginosa isolates from cystic fibrosis patients results in an increase in inflammatory response Cell Death & Disease, 2021-03-04;12(3):241. 2021-03-04 [PMID: 33664232] (Human)
• N Jones, J Blagih, F Zani, A Rees, DG Hill, BJ Jenkins, CJ Bull, D Moreira, AIM Bantan, JG Cronin, D Avancini, GW Jones, DK Finlay, KH Vousden, EE Vincent, CA Thornton Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation Nature Communications, 2021-02-22;12(1):1209. 2021-02-22 [PMID: 33619282] (Human)
• JI Alexander, DB Vendramini, R Francescon, T Luong, J Franco-Bar, N Shah, JC Gardiner, E Nicolas, KS Raghavan, E Cukierman Palladin isoforms 3 and 4 regulate cancer-associated fibroblast pro-tumor functions in pancreatic ductal adenocarcinoma Scientific Reports, 2021-02-15;11(1):3802. 2021-02-15 [PMID: 33589694] (Human)
• P Kvacskay, N Yao, JH Schnotz, R Scarpone, RA Carvalho, KD Klika, W Merkt, T Tretter, HM Lorenz, LO Tykocinski Increase of aerobic glycolysis mediated by activated T helper cells drives synovial fibroblasts towards an inflammatory phenotype: new targets for therapy? Arthritis Research & Therapy, 2021-02-15;23(1):56. 2021-02-15 [PMID: 33588937] (Human)
• Y Hosokawa, I Hosokawa, K Ozaki, T Matsuo The Polymethoxy Flavonoid Sudachitin Inhibits Interleukin-1&beta-Induced Inflammatory Mediator Production in Human Periodontal Ligament Cells BioMed Research International, 2021-01-28;2021(0):8826586. 2021-01-28 [PMID: 33575345] (Human)
• M Dabaghi, N Saraei, G Xu, A Chandiramo, J Yeung, JP Nguyen, M Vukmirovic, PR Selvaganap, JA Hirota PHAIR: a biosensor for pH measurement in air-liquid interface cell culture Scientific Reports, 2021-02-10;11(1):3477. 2021-02-10 [PMID: 33568708] (Human)
• MS Coates, EWFW Alton, GW Rapeport, JC Davies, K Ito Pseudomonas aeruginosa induces p38MAP kinase-dependent IL-6 and CXCL8 release from bronchial epithelial cells via a Syk kinase pathway PLoS ONE, 2021-02-01;16(2):e0246050. 2021-02-01 [PMID: 33524056] (Human)
• H Dai, O Penack, A Radujkovic, D Schult, J Majer-Laut, IW Blau, L Bullinger, S Jiang, C Müller-Tid, P Dreger, T Luft Early bilirubinemia after allogeneic stem cell transplantation-an endothelial complication Bone marrow transplantation, 2021-01-30;0(0):. 2021-01-30 [PMID: 33517355] (Human)
• SM Anil, N Shalev, AC Vinayaka, S Nadarajan, D Namdar, E Belausov, I Shoval, KA Mani, G Mechrez, H Koltai Cannabis compounds exhibit anti-inflammatory activity in vitro in COVID-19-related inflammation in lung epithelial cells and pro-inflammatory activity in macrophages Scientific Reports, 2021-01-14;11(1):1462. 2021-01-14 [PMID: 33446817] (Human)
• HJ Kim, KH Park, YM Kim, E Joo, K Ahn, S Shin A protein microarray analysis of amniotic fluid proteins for the prediction of spontaneous preterm delivery in women with preterm premature rupture of membranes at 23 to 30 weeks of gestation PLoS ONE, 2020-12-31;15(12):e0244720. 2020-12-31 [PMID: 33382822] (Human)
• LJ Williams, SG Tristram, GR Zosky Iron Oxide Particles Alter Bacterial Uptake and the LPS-Induced Inflammatory Response in Macrophages International Journal of Environmental Research and Public Health, 2020-12-28;18(1):. 2020-12-28 [PMID: 33379200] (Human)
• H Salvator, A Buenestado, M Brollo, E Naline, T Victoni, E Longchamp, H Tenor, S Grassin-De, P Devillier Clinical Relevance of the Anti-inflammatory Effects of Roflumilast on Human Bronchus: Potentiation by a Long-Acting Beta-2-Agonist Frontiers in Pharmacology, 2020-12-08;11(0):598702. 2020-12-08 [PMID: 33363471] (Human)
• R Kolahdouz-, F Shidfar, S Khodaverdi, T Arablou, S Heidari, N Rashidi, AA Delbandi Resveratrol treatment reduces expression of MCP-1, IL-6, IL-8 and RANTES in endometriotic stromal cells Journal of Cellular and Molecular Medicine, 2020-12-15;0(0):. 2020-12-15 [PMID: 33325132] (Human)
• EJ Dela Cruz, TL Fiedler, C Liu, MM Munch, CM Kohler, AR Oot, JM Wallis, J Wang, A Frishman, K Garcia, A Wiser, JE Balkus, S Srinivasan, JL Golob, LK Sycuro, JM Marrazzo, TR Hawn, DN Fredricks Genetic variation in Toll-like receptor-5 and colonization with flagellated bacterial vaginosis-associated bacteria Infect Immun, 2021-02-16;0(0):. 2021-02-16 [PMID: 33199356] (Human)
• M Kameda, M Otsuka, H Chiba, K Kuronuma, T Hasegawa, H Takahashi, H Takahashi CXCL9, CXCL10, and CXCL11; biomarkers of pulmonary inflammation associated with autoimmunity in patients with collagen vascular diseases-associated interstitial lung disease and interstitial pneumonia with autoimmune features PLoS ONE, 2020-11-02;15(11):e0241719. 2020-11-02 [PMID: 33137121] (Human)
• I Patlan, MP Jeffrey, D Lewis, J Green-John, S Dogra Salivary IL-8 and IL-1RA changes induced by exercise in cold-dry and normal conditions Cytokine, 2020-10-28;137(0):155347. 2020-10-28 [PMID: 33128925] (Human)
• S Niklander, D Bandaru, DW Lambert, KD Hunter ROCK inhibition modulates the senescence-associated secretory phenotype (SASP) in oral keratinocytes FEBS Open Bio, 2020-11-06;0(0):. 2020-11-06 [PMID: 33095981] (Human)
• M Tutter, C Schug, KA Schmohl, S Urnauer, C Kitzberger, N Schwenk, M Petrini, C Zach, S Ziegler, P Bartenstei, WA Weber, G Multhoff, E Wagner, LH Lindner, PJ Nelson, C Spitzweg Regional hyperthermia enhances mesenchymal stem cell recruitment to tumor stroma: Implications for mesenchymal stem cell-based tumor therapy Mol Ther, 2020-10-15;0(0):. 2020-10-15 [PMID: 33068779] (Human)
• T Peeters, S Martens, V D'Onofrio, MHT Stappers, JCH van der Hi, B Houben, R Achten, LAB Joosten, IC Gyssens An observational study of innate immune responses in patients with acute appendicitis Sci Rep, 2020-10-15;10(1):17352. 2020-10-15 [PMID: 33060696] (Human)
• G Kaufman, D Skrtic N-Acetyl Cysteine Modulates the Inflammatory and Oxidative Stress Responses of Rescued Growth-Arrested Dental Pulp Microtissues Exposed to TEGDMA in ECM Int J Mol Sci, 2020-10-03;21(19):. 2020-10-03 [PMID: 33023018] (Human)
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Review for CXCL8/IL-8 (DY208) (1)

Average Rating: 5

(Based on 1 review)

reviewed by: Patricia Carulla Martí 06/19/2023

Summary

• Sample Tested: Hacat cell culture supernatant,Human keratinocyte cell line (HaCat) culture
• Lot: P297345

Bioinformatics

• Gene Symbol: CXCL8