Recombinant Human IFN-beta Protein

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-99962
    • Availability
      Product Discontinued

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Recombinant Human IFN-beta Protein Summary

Description
A recombinant protein corresponding to 165 amino acids of Human IFN-beta
Preparation
Method
>98% SDS-PAGE
Details of Functionality
Biological Activity: Interferon B 1b is fully biologically active when compared to standard. The specific activity as determined in a viral resistance assay (human "Wish" cell line and VSV virus or the monkey VERO cell line with EMCV virus) was found to be 32 x 10^6 IU/ mg.
Protein/Peptide Type
Recombinant Protein
Gene
IFNB1
Purity
>98%, by SDS-PAGE
Endotoxin Note
<0.1 ng/ug

Applications/Dilutions

Theoretical MW
18.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
From 1 solution containing 50 mg human albumin and 50 mg dextrose.
Concentration
Lyoph
Purity
>98%, by SDS-PAGE
Reconstitution Instructions
Reconstitute with water to a final concentration of 0.1 - 1.0 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4C for 1 week or -20C for future use.

Notes

The purity of this protein is >95% pure by SDS-PAGE

Alternate Names for Recombinant Human IFN-beta Protein

  • Fibroblast interferon
  • IFB
  • IFBIFNB
  • IFF
  • IFNB
  • IFNB1
  • IFNbeta
  • IFN-beta
  • interferon beta
  • interferon, beta 1, fibroblast
  • MGC96956

Background

Recombinant Human IFN-Beta produced from E.Coli is a single, non-glycosylated human Interferon Beta -1b polypeptide chain containing 165 amino acids and having a molecular mass of 18.51 kDa. The Interferon Beta gene was cloned from human fibroblasts. IFN-Beta is purified by proprietary chromatographic techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Research Areas for IFN-beta Protein (NBP1-99962)

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Blogs on IFN-beta.

STING in Innate Immunity and Cancer: What’s the Buzz About?
STING (STimulator of INterferon Genes protein) acts as a sensor of cytosolic DNA. Bacteria/Virus or self-derived DNA in the cytosol activates the STING pathway and promotes the production of type I interferons (IFN-alpha and IFN-beta). STING also ...  Read full blog post.

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Bioinformatics

Gene Symbol IFNB1