IRF3 Antibody (3F10) [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, KO, Single-Cell Western
Clone
3F10
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

IRF3 Antibody (3F10) [Biotin] Summary

Immunogen
Recombinant human IRF3 (108-166aa) purified from E. coli
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
IRF3
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Knockout Validated
  • Single Cell Western
  • Western Blot
Readout System

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for IRF3 Antibody (3F10) [Biotin]

  • interferon regulatory factor 3
  • IRF3
  • IRF-3

Background

Members of the Interferon regulatory factor (IRF) family regulate gene expression critical to immune response, hemopoiesis, and proliferation. IRF-3 is a member of the IRF family, and is distinct from other family members. Its transcriptional activity is regulated solely by posttranslational modifications. It plays a crucial role in activation of innate immunity and inflammation in response to viral infection.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for IRF3 Antibody (NBP1-04308B). (Showing 1 - 1 of 1 FAQ).

  1. Hi, I am curious about the biotin-conjugated antibody NBP1-04308B. Do you have an estimate on how many biotins are conjugated?
    • There are 4-7 biotins per free amine. The free amines are located on lysines.

Secondary Antibodies

 

Isotype Controls

Additional IRF3 Products

Research Areas for IRF3 Antibody (NBP1-04308B)

Find related products by research area.

Blogs on IRF3.

TRIF/TICAM1 and mitochondrial dynamics in the innate immune response
TRIF, also known as toll like receptor adaptor molecule 1 or TICAM1, is known for its role in invading foreign pathogens as part of our innate immune response. TRIF/TICAM1 is a TIR-domain adaptor protein (toll/interleukin-1 receptor) that interacts...  Read full blog post.

STING in Innate Immunity and Cancer: What’s the Buzz About?
STING (STimulator of INterferon Genes protein) acts as a sensor of cytosolic DNA. Bacteria/Virus or self-derived DNA in the cytosol activates the STING pathway and promotes the production of type I interferons (IFN-alpha and IFN-beta). STING also ...  Read full blog post.

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Bioinformatics

Gene Symbol IRF3