MYBPC2 Antibody - BSA Free

Western Blot: MYBPC2 Antibody [NBP1-77133] - Analysis of MYBPC2 in mouse skeletal muscle tissue lysate with MYBPC2 antibody at (A) 1 and (B) 2 ug/mL.

Immunohistochemistry: MYBPC2 Antibody - BSA Free [NBP1-77133] - Immunohistochemistry of MYBPC2 in mouse skeletal muscle tissue with MYBPC2 antibody at 5 ug/mL.

• Reactivity: Hu, Mu, Ch
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

MYBPC2 Antibody - BSA Free Summary

• Immunogen: Antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human MYBPC2. The immunogen is located within amino acids 1070 - 1120 of MYBPC2. Amino Acid Squence: NKMEIREDPKFLITN
• Predicted Species: Chicken (91%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MYBPC2
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 1-2 ug/ml
• Control Peptide:

  MYBPC2 Peptide (NBP1-77133PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for MYBPC2 Antibody - BSA Free

• C-protein, skeletal muscle fast isoform
• fast MyBP-C
• fast-type muscle myosin-binding-protein C
• MGC163408
• MYBPC
• MYBPCF
• myosin binding protein C, fast type
• myosin-binding protein C, fast-type

Background

Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the fast-type isoform designated MYBPC2. Both the fast-type and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. MYBPC2 is typically required for strong contractions and functions under anaerobic conditions. It is more similar to the cardiac isoform (MYBPC3) than to the slow-type isoform (MYBPC1) in terms of pCa50-indexed force development, length-independent cooperativity and length dependent activation. It has been suggested that in cardiac and fast muscle MYBPC2 contributes to an internal load, possibly by binding to actin via its N-terminal region.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MYBPC2
• Uniprot:
  • EAW71866(Human)